Table 2.
Longitudinal change in cardiac structure and function in Patient 2.
| Year (time lapse after diagnosis) |
2016 (baseline) |
2018 (2 year) |
2020 (4 year) |
2022 (6 year) |
|---|---|---|---|---|
| LV septal thickness, mm | 11.2 | 10.9 | 8.4 | 8.3 |
| LV posterior wall thickness, mm | 10.7 | 10.5 | 8.4 | 8.7 |
| LV end-diastolic dimension, mm | 43.0 | 44.8 | 45.2 | 39.6 |
| LV mass index, g/m2 | 105.3 | 106.5 | 78.1 | 66.2 |
| LV EF, % | 60.9 | 64.3 | 56.6 | 51.2 |
| LV GLS, % | −14.8 | −13.4 | −14.1 | −14.4 |
| Mitral E velocity, cm/s | 81.2 | 77.2 | 91.34 | 63.2 |
| Mitral A velocity, cm/s | 53.7 | 55.9 | 58.03 | 53.6 |
| E’ velocity, cm/s | 11.6 | 12.3 | 13.0 | 7.8 |
| E/e’ ratio | 7.0 | 6.3 | 7.0 | 8.1 |
| HbA1C, % | 6.1 | 6.9 | 7.7 | 8.2 |
| Creatinine, mg/dL | 1.02 | 1.13 | 0.99 | 1.04 |
| eGFR, mL/min/1.73 m2 | 104.6 | 91.1 | 105.4 | 97.9 |
| NT-proBNP, pg/mL | 26.7 | 16.9 | 19.0 | 15.3 |