Table 3.

Eradication rates of each therapy group.

	VA (n = 78)	VBQT (n = 78)	Adjusted 95% CI for difference	P value for noninferiority†	P value for difference*
ITT	87.2% (68/78)	79.5% (62/78)	7.7%	.001	.195
95% CI	79.8% to 94.6%	70.5% to 88.4%	−3.9% to 19.3%
PP	94.4% (68/72)	96.8% (60/62)	−2.3%	.014	.507
95% CI	89.2% to 99.7%	92.4% to 100%	−9.2% to 4.6%

CI = confidence interval, ITT = intention-to-treat, PP = per protocol, VA = vonoprazan–amoxicillin dual therapy, VBQT = vonoprazan-based bismuth-containing quadruple therapy.

^*The P values were obtained from 2-sided comparisons of differences between the VA and VBQT groups. All results were considered significant if the P value was < .05.

^†The P values were obtained from 1-sided test comparisons of non-inferiority between the VA and VBQT groups. All results were considered significant if the P value was <.025.