Table 3.
Procedural outcomes of patients undergoing percutaneous coronary interventions for chronic total occlusion with and without contrast-associated acute kidney injury (CA-AKI).
| Variable | Overall (n = 2707) | No CA-AKI (n = 2395) | CA-AKI (n = 312) | P |
|---|---|---|---|---|
| Procedural success | 89.1% | 89.7% | 84.3% | 0.004 |
| Length of hospital stay [days]* | 2 (2, 2) | 2 (2, 2) | 2 (2, 3) | < 0.001 |
| Procedural time [min]* | 86 (54, 133) | 84 (53, 129) | 100 (65, 170) | < 0.001 |
| Fluoroscopy time [min]* | 37.0 (22.0, 65.0) | 36.0 (21.0, 63.0) | 47.5 (28.3, 82.0) | < 0.001 |
| Contrast volume [mL]* | 270 (200, 400) | 270 (200, 400) | 300 (200, 418) | < 0.001 |
| Dose area product [cGy × cm2]* | 10028 (5723, 17264) | 9770 (5660, 16639) | 12993 (6509, 22366) | < 0.001 |
| CV/eGFR [min]* | 3.72 (2.55, 5.48) | 3.63 (2.51, 5.29) | 4.96 (3.03, 7.83) | < 0.001 |
| CV/eGFR ratio > 3.7 | 50.5% | 48.7% | 65.1% | < 0.001 |
| Major complications‡ | 2.1% | 1.8% | 3.9% | 0.019 |
| In-hospital MACCE: | 1.3% | 1.3% | 1.6% | 0.655 |
| Death | 0.3% | 0.3% | 0.6% | 0.233 |
| MI | 0.2% | 0.3% | 0.0% | — |
| Stroke | 0.2% | 0.1% | 1.0% | 0.013 |
| TVR | 1.0% | 1.1% | 0.6% | 0.465 |
| TLR | 1.0% | 1.0% | 0.6% | 0.761 |
| Pericardial tamponade§ | 0.7% | 0.5% | 2.2% | 0.001 |
| Vascular access complication | 2.1% | 1.8% | 4.4% | 0.031 |
| Bleeding# | 2.5% | 2.0% | 6.9% | < 0.001 |
| Perforation | 2.4% | 2.3% | 3.2% | 0.324 |
*
Median (interquartile range);
‡
Composite of in-hospital major adverse cardiac and cerebrovascular events (MACCE) and pericardial tamponade requiring either pericardiocentesis or surgical evacuation;
§
Pericardial tamponade requiring pericardiocentesis or surgical evacuation;
#
Bleeding Academic Research Consortium (BARC) class 3 to 5;
CV — contrast volume; eGFR — estimated glomerular filtration rate; MI — myocardial infarction; TLR — target lesion revascularization; TVR — target vessel revascularization