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. 2024 Feb 20;41(3):msae036. doi: 10.1093/molbev/msae036

Table 3.

IGF1 sites potentially associated with body size. Sites within the IGF1 gene and flanking genomic regions that are significantly associated with body size in cetaceans

Site typea Small cetacean allele Large cetacean allele Blue whale chromosome 10 coordinate Genomic feature(s) Multiple alignment column
1 C T 85,170,164 Intergenic region 5′ of IGF1 24,474
1 A C 85,169,891 Intergenic region 5′ of IGF1; LINE element L2c 24,791
2 C T 85,160,822 Intron 2 35,626
2 G A 85,160,446 Intron 2 36,017
1 G C 85,150,447 Intron 2 48,867
1 A G 85,140,848 Intron 2; LINE element L2b 62,044
1 C T 85,140,276 Intron 2 62,965
2 C T 85,132,164 Intron 2; LINE element L2d 78,042
2 C T 85,126,807 Intron 2 87,228
1 G A 85,118,402 Intron 2 99,043
2 A G 85,112,779 Intron 3 106,724
1 C T 85,108,387 Intron 3-4 113,202

aSite type 1 is where 3 large whales, blue, minke, and sperm, have a different allele from all other artiodactyls (Fig. 5c). Type 2 is where smaller cetaceans have a different allele compared to the 4 largest whales, blue, minke, sperm, and orca, and terrestrial artiodactyls (Fig. 5d).