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. 2024 Jan 11;59(3):403–408. doi: 10.1038/s41409-023-02196-w

Table 2.

Events of cardiovascular disease in peripheral blood stem cell donors compared with age-, sex- and residence-matched controls.

New cardiovascular disease after time of donation PBSC donors Matched population controls
N = 1098 Number of events (%) Events/1000 person-years N = 5495 Number of events Events/1000 person-years Hazard ratio 95% Confidence Interval P-value
Any cardiovascular disease 1038 150 (14.5) 18.1 5022 755 (15.0) 19.2 0.89 0.75 1.06 0.19
Any cardiovascular disease, except hypertension 1065 113 (10.6) 11.3 5137 528 (10.3) 11.0 0.97 0.79 1.19 0.78
Hypertension 1067 95 (8.9) 9.4 5298 534 (10.1) 10.8 0.83 0.66 1.03 0.08
Any heart rhythm disease 1085 44 (4.1) 4.2 5408 231 (4.3) 4.5 0.92 0.67 1.27 0.61
Atrial Fibrillation 1091 24 (2.2) 2.3 5448 153 (2.8) 2.9 0.76 0.50 1.17 0.21
Myocardial infarction and/or Ischaemic heart disease 1085 31 (2.9) 2.9 5430 132 (2.5) 2.6 1.07 0.72 1.58 0.74
Myocardial Infarction 1094 19 (1.7) 1.8 5432 90 (1.7) 1.7 0.98 0.59 1.60 0.92
Ischaemic Heart Disease 1085 29 (2.7) 2.8 5358 126 (2.4) 2.4 0.95 0.63 1.42 0.80
Deep venous thrombosis and/or Pulmonary embolism 1098 17 (1.6) 1.6 5436 102 (1.9) 1.9 0.80 0.48 1.34 0.80
Deep venous thrombosis 1098 10 (0.9) 0.9 5447 66 (1.2) 1.3 0.73 0.38 1.42 0.35
Pulmonary embolism 1098 7 (0.6) 0.7 5480 47 (0.9) 0.9 0.72 0.33 1.59 0.42
Cardiac failure 1097 14 (1.3) 1.3 5464 93 (1.7) 1.8 0.73 0.41 1.28 0.26
Cerebrovascular disease 1094 15 (1.4) 1.4 5435 121 (2.2) 2.3 0.59 0.35 1.01 0.06