Table 3.
Events of cardiovascular disease in peripheral blood stem cell donors compared with bone marrow donors.
| New cardiovascular disease after time of donation | PBSC donors | BM donors | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| N = 1098 | Number of events (%) | Events/1000 person-years | N = 854 | Number of events (%) | Events/1000 person-years | Hazard ratio | 95% Confidence Interval | P-value | ||
| Any cardiovascular disease | 1038 | 150 (14.5) | 15.7 | 841 | 153 (18.2) | 10.0 | 0.90 | 0.63 | 1.27 | 0.90 |
| Any cardiovascular disease, except hypertension | 1065 | 113 (10.6) | 11.3 | 844 | 114 (13.5) | 7.3 | 0.94 | 0.62 | 1.40 | 0.75 |
| Hypertension | 1067 | 95 (8.9) | 9.4 | 848 | 85 (10.0) | 5.3 | 0.82 | 0.51 | 1.30 | 0.39 |
| Any heart rhythm disease | 1085 | 44 (4.1) | 4.2 | 852 | 53 (6.2) | 3.3 | 0.87 | 0.47 | 1.64 | 0.67 |
| Atrial Fibrillation | 1091 | 24 (2.2) | 2.3 | 854 | 28 (3.3) | 1.7 | 0.89 | 0.44 | 1.79 | 0.73 |
| Myocardial infarction and/or Ischaemic heart disease | 1085 | 31 (2.9) | 2.9 | 850 | 28 (3.3) | 1.7 | 1.12 | 0.49 | 2.58 | 0.79 |
| Myocardial Infarction | 1094 | 19 (1.7) | 1.8 | 853 | 14 (1.6) | 0.9 | 1.00 | 0.37 | 3.21 | 0.88 |
| Ischaemic Heart Disease | 1085 | 29 (2.7) | 2.8 | 850 | 25 (2.9) | 1.5 | 1.37 | 0.55 | 3.47 | 1.37 |
| Deep venous thrombosis and/or Pulmonary embolism | 1098 | 17 (1.6) | 1.6 | 854 | 17 (2.0) | 1.0 | 0.85 | 0.31 | 2.36 | 0.76 |
| Deep venous thrombosis | 1098 | 10 (0.9) | 0.9 | 853 | 13 (1.5) | 0.8 | 0.60 | 0.18 | 1.96 | 0.40 |
| Pulmonary embolism | 1098 | 7 (0.6) | 0.7 | 854 | 8 (0.9) | 0.5 | 1.71 | 0.30 | 9.68 | 0.55 |
| Cardiac failure | 1097 | 14 (1.3) | 1.3 | 854 | 15 (1.8) | 0.9 | 3.12 | 0.71 | 13.78 | 0.13 |
| Cerebrovascular disease | 1094 | 15 (1.4) | 1.4 | 853 | 19 (2.2) | 1.2 | 0.69 | 0.24 | 2.05 | 0.51 |