Table 4.
Univariable and multivariable analysis for neonatal outcomes.
| No maternal CHD (n = 15,720) | Maternal CHD (n = 3930) | Crude OR (95% CI) | Adjustedc OR (95% CI) | |
|---|---|---|---|---|
| 1-year mortality | 0.3% | 0.7% | 2.32 (1.47–3.69) | 1.27 (0.77–2.07) |
| Major neonatal morbiditya | 0.7% | 1.7% | 2.48 (1.82–2.28) | 1.53 (1.10–2.14) |
| PPHN | 0.3% | 0.8% | 2.57 (1.62–4.06) | 1.57 (0.96–2.60) |
| Need for NIPPV or IPPV during birth hospitalization | 3.7% | 7.9% | 2.21 (1.91–2.55) | 1.64 (1.40–1.92) |
| Long birth hospitalizationb | 12.4% | 20.1% | 1.77 (1.62–1.94) | 1.48 (1.34–1.64) |
| Hospital readmission during first year of life | 10.7% | 13.5% | 1.30 (1.17–1.49) | 1.13 (1.01–1.26) |
PPHN persistent pulmonary hypertension of the newborn, NIPPV non-invasive positive pressure ventilation, IPPV invasive positive pressure ventilation, OR odds ratio, CHD congenital heart disease, CI confidence interval.
aDefined as one of the following: bronchopulmonary dysplasia, severe retinopathy of prematurity requiring intervention, intraventricular hemorrhage >grade 2, necrotizing enterocolitis.
bFor vaginal delivery length of stay >2 days, for c-section length of stay >4 days.
cadjusted for gestational age, sex, small for gestational age, critical congenital heart disease, and other malformations or syndromes.