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. 2023 Jul 18;95(4):1095–1100. doi: 10.1038/s41390-023-02729-5

Table 1.

Comparison between patient and control groups regarding GDF15, hepcidin, and erythroferrone.

Control group No. = 60 Patients group No. = 61 P value
GDF15 by PCR N (CC) 44 (73.3%) 32 (52.5%) 0.035
HT (CG) 16 (26.7%) 27 (44.3%)
H (GG) 0 (0.0%) 2 (3.3%)
GDF15 (ng/ml) Median (IQR) 59 (35–98.1) 576.5 (182.6–1200.5) <0.001
Range 7.8–218 10.5–4842.4
Erythroferrone (ng/ml) Median (IQR) 159.6 (86.7–349.1) 992.4 (215–1571.4) <0.001
Range 15.2–5021 48.4–5803.8
Hepcidin (ng/ml) Median (IQR) 2130 (1139.2–5464) 535.7 (336.4–814.1) <0.001
Range 346.7–12,164.1 99.3–13,053.9

N CC normal (wild type), Ht CG heterozygous, H GG homozygous, GDF15 growth differentiation factor 15, PCR polymerase chain reaction, SD standard deviation, IQR interquartile range.