Table 1.
Control group No. = 60 | Patients group No. = 61 | P value | ||
---|---|---|---|---|
GDF15 by PCR | N (CC) | 44 (73.3%) | 32 (52.5%) | 0.035 |
HT (CG) | 16 (26.7%) | 27 (44.3%) | ||
H (GG) | 0 (0.0%) | 2 (3.3%) | ||
GDF15 (ng/ml) | Median (IQR) | 59 (35–98.1) | 576.5 (182.6–1200.5) | <0.001 |
Range | 7.8–218 | 10.5–4842.4 | ||
Erythroferrone (ng/ml) | Median (IQR) | 159.6 (86.7–349.1) | 992.4 (215–1571.4) | <0.001 |
Range | 15.2–5021 | 48.4–5803.8 | ||
Hepcidin (ng/ml) | Median (IQR) | 2130 (1139.2–5464) | 535.7 (336.4–814.1) | <0.001 |
Range | 346.7–12,164.1 | 99.3–13,053.9 |
N CC normal (wild type), Ht CG heterozygous, H GG homozygous, GDF15 growth differentiation factor 15, PCR polymerase chain reaction, SD standard deviation, IQR interquartile range.