Table 3.
Comparison of asymmetry indexes for language-related regions between children born EPT and term-born controls using generalized estimating equations.
| Brain region asymmetry | Children born EPT (n = 50) | Term-born controls (n = 37) | Mean difference, (95% CI), adjusted | p-value adjusted | Side dominance |
|---|---|---|---|---|---|
| Supplementary motor area, mean (SD) AI | –4.93 (0.45) | –4.93 (0.42) | –0.004 (–0.19, 0.18) | 0.97 | Right |
| Inferior frontal gyrus, triangular, mean (SD) AI | 7.62 (0.30) | 7.68 (0.27) | –0.055 (–0.18, 0.071) | 0.37 | Left |
| Inferior frontal gyrus, opercular, mean (SD) AI | –17.33 (0.56) | –17.28 (0.40) | –0.046 (–0.24, 0.15) | 0.65 | Right |
| Heschl’s gyrus, mean (SD) AI | –5.82 (1.10) | –6.08 (1.30) | 0.26 (–0.29, 0.80) | 0.35 | Right |
| Angular gyrus, mean (SD) AI | –24.44 (0.35) | –24.31 (0.49) | –0.020 (–0.19, 0.15) | 0.82 | Right |
| Supramarginal gyrus, mean (SD) AI | –26.06 (0.49) | –26.05(0.90) | –0.010 (–0.21, 0.19) | 0.93 | Right |
| Superior temporal gyrus, mean (SD) AI | –18.06 (0.32) | –18.16 (0.55) | –0.11 (–0.93, 0.31) | 0.29 | Right |
| Middle temporal gyrus, mean (SD) AI | 2.63 (0.19) | 2.67 (0.30) | –0.046 (–0.16, 0.07) | 0.42 | Left |
| Inferior temporal gyrus, mean (SD) AI | –8.98 (0.25) | –8.89 (0.31) | –0.82 (–0.20, 0.042) | 0.19 | Right |
| Summed language regions, mean (SD) AI | –8.07 (0.091) | –8.05 (0.10) | –0.21(–0.061, 0.022) | 0.32 | Right |
Results adjusted for sex, intracranial volume, and age at MRI.