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. 2024 Feb 23;15:1343337. doi: 10.3389/fendo.2024.1343337

Table 2.

Food consumption and dietary eating patterns of the ISS children and their siblings according to the gut microbiome analysis.

Characteristic All Participants ISS Subgroup-S1 ISS Subgroup-S2
Subjects Siblings P Subjects Siblings P1 Subjects Siblings P2 P 1vs.2
A. Food consumption
Number 28 27 13 12 15 15
Number of meals/day 4.7 (4.7, 5.0) 5.0 (4.7, 5.3) 0.229 4.7 (4.7, 5.0) 5.0 (4.7, 5.0) 0.179 5.0 (4.3, 5.1) 5.0 (4.6, 5.7) 0.561 0.565
Energy/wt (Kcal/kg/day) 75.3 ± 15.5 70.4 ± 23.3 0.357 73.0 ± 16.9 66.0 ± 16.7 0.310 77.3 ± 14.5 73.9 ± 27.5 0.670 0.468
Protein/wt (gr/kg/day) 3.2 ± 0.8 2.9 ± 1.2 0.312 3.1 ± 0.9 2.7 ± 0.8 0.191 3.2 ± 0.8 3.0 ± 1.4 0.753 0.946
% Kcals from Proteins 16.8 ± 2.7 16.1 ± 2.3 0.303 17.2 ± 2.6 16.3 ± 2.2 0.327 16.5 ± 2.9 16.0 ± 2.5 0.628 0.475
Dairy/total proteins (%) 20.7 ± 9.7 20.9 ± 10.9 0.932 19.1 ± 8.8 18.0 ± 10.2 0.772 22.1 ± 10.6 23.3 ± 11.3 0.762 0.427
Meat/total proteins (%) 41.2 ± 15.8 38.7 ± 14.4 0.547 43.6 ± 13.5 41.1 ± 11.8 0.629 39.1 ± 17.7 36.8 ± 16.4 0.713 0.460
Fat/wt (gr/kg/day) 2.5 ± 0.6 2.2 ± 0.8 0.161 2.4 ± 0.7 2.0 ± 0.4 0.085 2.5 ± 0.6 2.4 ± 1.0 0.597 0.679
% Kcals from fats 29.9 ± 4.4 28.7 ± 3.8 0.280 30.1 ± 4.6 28.2 ± 3.1 0.241 29.8 ± 4.4 29.1 ± 4.4 0.686 0.856
Carbs/wt (gr/kg/day) 9.7 ± 2.2 9.4 ± 3.0 0.660 9.4 ± 2.2 9.0 ± 2.6 0.705 10.1 ± 2.2 9.8 ± 3.4 0.779 0.442
% Kcals from carbs 51.8 ± 5.9 53.8 ± 4.3 0.166 51.7 ± 5.9 54.3 ± 4.5 0.238 52.0 ± 6.1 53.4 ± 4.3 0.449 0.914
Zinc (% RDA) 100.3
(82.6, 130.4)
133.6
(98.6, 186.8)
0.080 85.9
(75.4,122.1)
128.4
(76.1, 175.1)
0.384 110.0
(97.2,133.4)
142.4
(101.7,200.3)
0.152 0.076
Iron (% RDA) 83.0
(64.9, 115.4)
74.1
(61.9, 116.0)
0.692 80.6
(66.4,121.0)
79.0
(53.4, 128.8)
0.624 83.2
(62.1,103.2)
74.1
(71.3,94.7)
0.604 0.945
Calcium (% RDA) 50.3 ± 24.6 53.3 ± 23.1 0.647 53.1 ± 30.9 46.6 ± 21.6 0.549 47.9 ± 18.5 58.7 ± 23.6 0.175 0.589
B. Dietary eating patterns
Number 29 29 14 14 15 15
Food responsiveness 1.4 (1.2, 1.7) 1.6 (1.4, 2.5) 0.004 1.3 (1.2, 1.8) 2.0 (1.4, 3.0) 0.039 1.4 (1.2, 1.6) 1.5 (1.4, 2.0) 0.045 0.747
Enjoyment of food 3.0 (2.3, 3.5) 3.5 (2.9, 4.0) 0.019 2.8 (2.3, 3.6) 3.4 (3.0, 4.0) 0.024 3.0 (2.0, 3.5) 3.5 (2.8, 4.0) 0.300 0.893
Emotional overeating 1.3 (1.0, 2.0) 1.5 (1.0, 2.3) 0.464 1.3 (1.0, 2.0) 1.3 (1.0, 2.5) 0.571 1.5 (1.0, 2.0) 1.8 (1.0, 2.0) 0.797 0.687
Desire to drink 1.7 (1.3, 2.8) 2.0 (1.5, 3.5) 0.214 1.8 (1.3, 2.8) 2.7 (1.7, 3.7) 0.164 1.7 (1.3, 3.0) 2.0 (1.3, 3.0) 0.748 0.767
Satiety responsiveness 3.8 (3.4, 4.2) 2.6 (2.4, 3.6) <0.001 3.7 (3.4, 4.3) 2.6 (2.4, 3.3) 0.001 4.0 (3.4, 4.2) 3.2 (2.6, 3.8) 0.019 0.715
Slowness of eating 3.3 (2.9, 4.0) 2.5 (2.0, 3.0) <0.001 3.1 (2.9, 3.6) 2.3 (2.0, 3.0) 0.011 3.5 (2.8, 4.3) 2.5 (2.3, 3.0) 0.002 0.451
Emotional under eating 2.8 (2.0, 3.3) 2.5 (2.0, 3.4) 0.938 2.9 (1.9, 3.3) 2.8 (1.9, 3.6) 0.946 2.8 (2.3, 3.3) 2.5 (2.0, 3.0) 0.748 0.999
Food fussiness 3.3 (2.3, 3.8) 3.0 (2.2, 3.8) 0.846 3.4 (2.3, 4.0) 3.7 (2.8, 4.0) 0.734 3.3 (2.2, 3.7) 2.3 (2.2, 3.7) 0.436 0.477

P1 represents comparisons between subjects from ISS subgroup-S1 and their siblings. P2 represents comparisons between subjects from ISS subgroup-S2 and their siblings. P1 vs. P2 represents comparisons between subjects from ISS subgroup-S1 and subjects from ISS subgroup-S2. A: Food consumption by the ISS children and their siblings subdivided according to the gut microbiota analysis B: Dietary intake patterns by the ISS children and their siblings subdivided according to the gut microbiota analysis.

Bold indicates significant.

ISS, idiopathic short stature; RDA- recommended dietary allowance.