Table 2.

Multivariate regression analysis associating quintiles of ambient temperature with eGFR in different vulnerability groups

	No. of measurements	Bivariable regression		Multivariable regression
		Coefficient  = Change in eGFR in ml/min (SE)	P Value	Coefficient  = Change in eGFR in ml/min (SE)	P Value
Vulnerability (at T < 15 °C)
0	5658	0.00
1	18,931	−8.46 (0.27)	0.000	−5.4 (0.3)	0.000
2	24,048	−21.42 (0.29)	0.000	−15.6 (0.3)	0.000
3	14,396	−37.54 (0.32)	0.000	−29.4 (0.3)	0.000
4	4220	−56.29 (0.37)	0.000	−46.4 (0.4)	0.000
5	501	−77.12 (0.68)	0.000	−65.1 (0.7)	0.000
Vulnerability 0
< 15 °C	5658	0.00		0.0
15–20 °C	2054	−0.38 (0.08)	0.000	−0.2 (0.3)	0.359
20–25 °C	1744	−0.71 (0.08)	0.000	−0.4 (0.3)	0.116
25–30 °C	1099	−0.70 (0.10)	0.000	−0.7 (0.3)	0.030
≥ 30 °C	357	−1.01 (0.16)	0.000	0.0 (0.53)	0.958
Vulnerability 1
15–20 °C	6963			−0.2 (0.3)	0.424
20–25 °C	6106			−0.2 (0.3)	0.602
25–30 °C	3716			0.3 (0.4)	0.445
≥ 30 °C	1178			−1.0 (0.6)	0.106
Vulnerability 2
15–20 °C	8719			0.0 (0.3)	0.979
20–25 °C	7642			−0.1 (0.3)	0.793
25–30 °C	4737			0.0 (0.4)	0.989
≥ 30 °C	1509			−0.7 (0.6)	0.224
Vulnerability 3
15–20 °C	5295			0.0 (0.3)	0.995
20–25 °C	4874			−0.3 (0.3)	0.306
25–30 °C	2984			−0.2 (0.4)	0.678
≥ 30 °C	948			−1.5 (0.6)	0.015
Vulnerability 4
15–20 °C	1500			−0.4 (0.4)	0.244
20–25 °C	1396			−0.4 (0.4)	0.269
25–30 °C	855			−0.4 (0.4)	0.374
≥ 30 °C	261			−1.9 (0.7)	0.010
Vulnerability 5
15–20 °C	501			0.8 (0.7)	0.287
20–25 °C	198			0.4 (0.8)	0.629
25–30 °C	164			−2.9 (1.0)	0.003
≥ 30 °C	91			−1.4 (1.5)	0.365

Analysis based on dataset B (n = 114 176)

Changes in eGFR values according to temperature groups that reached significance in the multivariable regression and corresponding P values are marked in bold