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. 2023 Nov 28;55(1):1011–1015. doi: 10.1007/s42770-023-01175-z

Table 2.

Inhibitory concentration fraction index (FICi) values of bioactive compounds interacting with antimicrobials showed synergism

Checkerboard FICi
UFV03 J
Tiamulin × Gut-A 0.2A 0.34A
Valnemulin × 7-Epic- Cu 0.56B 0.54B
Valnemulin × Gut-A 0.3A 0.4A
Enrofloxacin × 7- Epic 0.5A 0.55B
Enrofloxacin × 7-Epic- Cu 0.3A 0.3A

All other interactions tested did not show a synergistic effect, with interaction index indices in the range of 0.75 < FICi ≤ 2

ATotal synergism

BPartial synergism