Table 3.
Open-angle vs. closed-angle uveitic glaucoma.
| Sociodemographic and clinical characteristics | Open-angle glaucoma N = 86 (%) Median (IQR 25–75%) | Closed-angle Glaucoma N = 22 (%) Median (IQR 25–75%) | P-valuea |
|---|---|---|---|
| Age of first uveitis episode | 48.0 (34.0–64.0) | 56.0 (33.0–67.0) | 0.520 |
| Female | 49 (57.0%) | 12 (54.5%) | 0.837 |
| Male | 37 (43.0%) | 10 (43.5%) | |
| Aetiology | n(%) | n(%) | 0.38 |
| Idiopathic | 13 (15%) | 5 (23%) | |
| Toxoplasmosis | 5 (5.8%) | 1 (4.5%) | |
| Herpes simplex virus | 5 (5.8%) | 1 (4.5%) | |
| Juvenile idiopathic arthritis | 3 (3.5%) | 0 (0%) | |
| HLA-B27+ | 2 (2.3%) | 0 (0%) | |
| Cytomegalovirus | 2 (2.3%) | 0 (0%) | |
| Tuberculosis | 2 (2.3%) | 0 (0%) | |
| Mixed connective tissue disease | 2 (2.3%) | 0 (0%) | |
| Sarcoidosis | 1 (1.2%) | 1 (4.5%) | |
| Post-traumatic Uveitis | 1 (1.2%) | 1 (4.5%) | |
| Rheumatoid arthritis | 1 (1.2%) | 1 (4.5%) | |
| Herpes zoster virus | 1 (1.2%) | 1 (4.5%) | |
| Multiple Sclerosis | 1 (1.2%) | 0 (0%) | |
| Psoriasis | 1 (1.2%) | 0 (0%) | |
| Sjögren syndrome | 1 (1.2%) | 0 (0%) | |
| Reactive arthritis | 1 (1.2%) | 0 (0%) | |
| Post-traumatic Uveitis | 1 (1.2%) | 0 (0%) | |
| Fuchs’ heterochromic iridocyclitis | 1 (1.2%) | 0 (0%) | |
| Granulomatosis with polyangiitis | 1 (1.2%) | 0 (0%) | |
| Viral unspecific | 1 (1.2%) | 0 (0%) | |
| Suspect Behçet | 1 (1.2%) | 0 (0%) | |
| Crohn’s disease | 0 (0%) | 1 (4.5%) | |
| Ocular lymphoma | 0 (0%) | 1 (4.5%) | |
| Undetermined | 37 (43%) | 6 (27%) | |
| Highest IOP (IQR 25th and 75th) [Range] | 27 (18.0–35.0) [8–56] | 28 (15.0–36.0) [6–62] | 0.962 |
| Final IOP | 15 (14.0–19.3) | 16 (13.0– 20.0) | 0.838 |
| Last visit Cup/Disk ratio | 0.5 (0.35–0.9) | 0.7 (0.55–0.8) | 0.622 |
| Corneal oedema | 12 (14.63%) | 3 (3.65%) | 0.847 |
| Abnormal VF | 38 (%) | 8 (%) | 0.554 |
| Abnormal OCT | 38 (%) | 4 (6%) | 0.748 |
| Number of hypotensive agents | 3.0 (2.0–3.0) | 2.5 (1.2–3.0) | 0.303 |
| Need for a surgical procedure | 43 (%) | 8 (%) | 0.283 |
aA t test or Mann–Whitney test was used for continuous variables and a Chi-square (χ2) test or Fisher’s exact test for categorical variables according to their distribution.