Table 2.
Baseline pathological characteristics stratified by Oxford T lesions of IgAN patients
| Variables | T0 (n ) |
T1/2(n ) |
P |
|---|---|---|---|
| Age (years) | 33(27, 42) | 37(31, 46) | 0.018 |
| Men, n (%) | 59(28.37) | 34(41.46) | 0.023 |
| BMI (kg/m2) | 22.15(20.53, 24.80) | 23.35(21.08, 25.80) | 0.072 |
| Hypertension, n (%) | 46(22.12) | 52(63.41) |
 0.001 |
| UPE (g/d) |
 0.001 |
||
| <1 | 164(78.84) | 21(25.61) | |
| 1-3.5 | 38(18.27) | 41(50.00) | |
| ≥3.5 | 6(2.88) | 20(24.39) | |
| Hematuria (RBCs/ul) | 58.00(19.00,176.50) | 45.00(14.75,104.00) | 0.205 |
| Serum creatinine (μmol/L) | 78.00(66.00, 96.00) | 17.50(117.75, 229.75) |
 0.001 |
| Serum albumin (g/L) | 37.50(34.20, 40.55) | 34.60(30.28, 38.80) |
 0.001 |
| Serum cystatin C | 0.88(0.75, 1.07) | 1.61(1.28, 2.43) |
 0.001 |
| Hs-CRP (mg/L) | 0.69(0.30, 1.74) | 0.96(0.34, 3.06) | 0.094 |
| eGFRcr-cys (mL/min/1.73m2) | 95.39(77.55, 108.14) | 40.21(22.08, 61.42) |
 0.001 |
| Serum IgG (g/L) | 12.15(10.23, 13.88) | 10.85(8.48, 13.83) | 0.008 |
| Serum IgA (g/L) | 3.25(2.51, 3.98) | 2.89(2.46, 4.03) | 0.296 |
| Serum IgM (g/L) | 1.12(0.82, 1.49) | 0.97(0.71, 1.37) | 0.049 |
| Serum C3 (mg/L) | 1040.00(929.25, 1170.00) | 1030.00(916.25, 1142.50) | 0.677 |
| Serum C4 (mg/L) | 237.00(198.00, 289.00) | 278.00(222.75, 336.75) |
 0.001 |
Results are presented as mean SD, median (interquartile range), or number (percentage).
Groups were compared by using Kruskal-Wallis or F test
BMI body mass index; UPE urinary protein excretion; eGFR estimated glomerular filtration rate; hs-CRP high-sensitivity C-reactive protein; MEST-C, M mesangial hypercellularity; E endocapillary hypercellularity; S segmental glomerulosclerosis; T interstitial fibrosis/tubular atrophy; C crescent formation.