Table 2.
Effect of DEME on Body Weight Level of STZ-induced rats.
| Groups |
Body Weight (g) in days |
||
|---|---|---|---|
| Day 1 | Day 14 | Change in Body weight | |
| Normal Control | 209.6 ± 2.08 | 258 ± 8.0 | 48.4 |
| Negative Control | 212.2 ± 1.9 | 151.3 ± 8.2a | −60.9 |
| Standard (Glibenclamide) | 215 ± 3.03 | 297.7 ± 13.6b | 82.7 |
| DEME 200 mg/kg | 210.4 ± 4.07 | 274 ± 25.4b | 63.6 |
| DEME 400 mg/kg | 214.2 + 4.15 | 249.3 ± 19.03b | 35.1 |
Values are mean ± S.E.M of six (6) animals. Superscript represents the significance by ANOVA, followed with Tukey’s multiple comparison test. a P < 0.001, is the significant induction of diabetes in the negative diabetic control group when compared to the normal control animal group. b P < 0.001, is the significant improvement from the diabetic conditions on comparison of negative control (STZ injected) animals with the treated animal groups such as standard drug, DEME 200 and 400 mg/kg, respectively.