Table 3.
Effect of the DEME on Blood Glucose Level in STZ-Induced Diabetic Rats Weekly.
| Groups |
Blood glucose levels (mg/dl) |
||
|---|---|---|---|
| Day 1 | Day 7 | Day 14 | |
| Normal Control | 81.5 ± 3.93 | 83.5 ± 4.33 | 83 ± 3.74 |
| Negative Control | 376.3 ± 50.34 | 613 ± 89.23a | 459.7 ± 38.95a |
| Standard (Glibenclamide) | 293 ± 39.04 | 212.2 ± 28.22b | 163 ± 31.9b |
| DEME 200 mg/kg | 243.5 ± 26.15 | 151.3 ± 20.55b | 130.6 ± 14.84b |
| DEME 400 mg/kg | 275.7 ± 14.63 | 179.7 ± 26.32b | 147.0 ± 25.65b |
Values are mean ± S.E.M of six animals. Superscript represents the significance by ANOVA, followed by Tukey’s multiple comparison test. a P < 0.001, is the significant induction of diabetes in the negative diabetic control group when compared to the normal control animal group. b P < 0.001, is the significant improvement from the diabetic conditions on comparison of negative control (STZ injected) animals with the treated animal groups such as standard drug, DEME 200 and 400 mg/kg, respectively.