Figure 7.

PolyAMiner-Bulk analysis of the bulk RNA-seq dataset of skin fibroblasts with and without siRNA-mediated knockdown of NUDT21

(A) Volcano plot of differential APA genes.

(B) UpSet plot analysis of PolyAMiner-Bulk results against previously published results.

(C) NUDT21 motif and biding analysis of the unique 3′ UTR shortening genes identified by PolyAMiner-Bulk.

(D) Representative differential APA gene identified by PolyAMiner-Bulk but not the previously published study.

(E) Representative differential APA gene identified by the previously published study but not PolyAMiner-Bulk.

(F) Panther Pathway over-representation analysis of the differential APA genes identified by PolyAMiner-Bulk.

(G) Gene Ontology (GO:Biological Process over-representation analysis of the differential APA genes identified by PolyAMiner-Bulk.