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. 2024 Jan 15;15(1):1–6. doi: 10.30466/vrf.2023.2007263.3988

Table 1.

Comparison of plasma marbofloxacin concentrations following single-dose oral administration (5.00 mg kg-1 body weight) in Group I (non-pre-treated; n = 8) and Group II (pre-treated with alpha-1-monolaurin; n = 8)

Time after administration (hr) Concentrations (µg mL -1 )
Group I Group II
0.083 0.42 ± 0.06 0.38 ± 0.07
0.25 0.61 ± 0.18 0.82 ± 0.18
0.5 0.97 ± 0.18 1.44 ± 0.29
1 1.61 ± 0.21 2.19 ± 0.29*
2 1.77 ± 0.14 2.09 ± 0.21*
4 0.97 ± 0.13 1.20 ± 0.10
8 0.59 ± 0.06 0.69 ± 0.06
12 0.37 ± 0.06 0.33 ± 0.02
24 0.10 ± 0.04 0.18 ± 0.02*
36 ND ND
48 ND ND

ND: Not detected.

* indicates statistically significant difference at p ≤ 0.05.