Table 2.
Brain regions with significant differences in fractional amplitude of low frequency fluctuations, regional homogeneity and independent component analysis between adolescents with major depression disorders and healthy controls
Indices
|
Anatomical region
|
MNI coordinates, x, y, z
|
Peak intensity
|
Cluster size
|
fALFF of WM | Posterior limb of the internal capsule L | 21, -18, 3 | -6.12 | 27 |
Posterior corona radiata R | -24, -39, 33 | -5.57 | 36 | |
Body of the corpus callosum | 12, 15, 30 | -5.75 | 62 | |
Superior corona radiata R | -18, -21, 51 | -5.44 | 71 | |
Posterior corona radiata L | 24, -36, 39 | -6.39 | 106 | |
ReHo of WM | Posterior limb of the internal capsule R | 27, 0, 18 | 5.40 | 60 |
Superior corona radiata L | -27, 3, 39 | 4.55 | 23 | |
Superior longitudinal fasciculus L | -30, -39, 42 | -5.33 | 18 | |
Superior longitudinal fasciculus L | -24, -24, 48 | -4.76 | 14 | |
ICA of WM | Posterior limb of the internal capsule R | 27, -15, 12 | 4.30 | 26 |
Superior longitudinal fasciculus L | -24, -24, 45 | -5.80 | 25 |
The significance threshold was set at P < 0.001, FWE voxel correction for multiple comparisons. fALFF: Fractional amplitude of low frequency fluctuations; WM: White matter; ReHo: Regional homogeneity; ICA: Independent component analysis; L: Left; R: Right; MNI: Montreal neurological institute.