Table 2.

Sugar Intake by quintiles and Alzheimer’s disease dementia risk

	Median Intake; N (grams/day)	Model 1	Model 1 + MIND diet	Model 1 + MIND diet + Physical activity
		Total sugar intake
Q1	71 grams/day; N = 158	Ref	Ref	Ref
Q3 HR (95% CI)	102 grams/day; N = 158	1.30 (0.67, 2.53)	1.39 (0.71, 2.72)	1.42 (0.72, 2.780)
Q5 HR (95% CI)	133 grams/day; N = 158	1.77 (0.90, 3.46)	2.04 (1.03, 4.06)	2.10 (1.05, 4.19)
p-trend		0.19	0.09	0.08
		Sucrose Intake
Q1	27 grams/day; N = 158	Ref		Ref
Q3 HR (95% CI)	41 grams/day; N = 159	1.40 (0.75, 2.62)	1.39 (0.74, 2.59)	1.33 (0.71, 2.50)
Q5 HR (95% CI)	58 grams/day; N = 159	1.95 (1.07, 3.59)	1.90 (1.04, 3.48)	1.93 (1.05, 3.54)
p-trend		0.11	0.13	0.11
		Maltose Intake
Q1	1.0 grams/day; N = 158	Ref		Ref
Q3 HR (95% CI)	1.6 grams/day; N = 159	0.97 (0.55, 1.71)	0.98 (0.56, 1.72)	0.97 (0.55, 1.70)
Q5 HR (95% CI)	2.5 grams/day; N = 158	0.97 (0.54, 1.76)	0.93 (0.51, 1.69)	0.94 (0.52, 1.72)
p-trend		0.92	0.78	0.80
		Lactose Intake
Q1	5 grams/day; N = 158	Ref	Ref	Ref
Q3 HR (95% CI)	15 grams/day; N = 158	1.27 (0.68, 2.38)	1.87 (0.99, 3.51)	1.39 (0.74, 2.63)
Q5 HR (95% CI)	30 grams/day; N = 158	1.33 (0.68, 2.62)	1.45 (0.73, 2.86)	1.43 (0.72, 2.84)
p-trend		0.69	0.53	0.60
		Fructose Intake
Q1	13 grams/day; N = 158	Ref	Ref	Ref
Q3 HR (95% CI)	22 grams/day; N = 158	1.96 (1.03, 3.72)	2.26 (1.17, 4.34)	2.26 (1.17, 4.35)
Q5 HR (95% CI)	33 grams/day; N = 159	2.21 (1.12, 4.36)	2.77 (1.37, 5.58)	2.80 (1.38, 5.67)
p-trend		0.14	0.033	0.028
		Glucose Intake
Q1	12 grams/day; N = 158	Ref	Ref	Ref
Q3 HR (95% CI)	19 grams/day; N = 157	1.65 (0.890, 3.03)	1.85 (0.99, 3.43)	1.77 (0.95, 3.31)
Q5 HR (95% CI)	28 grams/day; N = 159	1.53 (0.77, 3.02)	1.82 (0.91, 3.67)	1.84 (0.91, 3.71)
p-trend		0.42	0.18	0.17

(N = 786; Cox proportional hazards models). Model 1 is controlled for age, sex, education, APOE ε4 status, total calories from non-sugar sources.