Table 3.
Correlation coefficients between habitual physical activity, the intensity of habitual physical activity, and clinical outcomes (A) and between changes in habitual physical activity, the intensity of habitual physical activity, and clinical outcomes (B) in the ETI group and in the non-ETI group.
| ETI group (n = 21) | non-ETI group (n = 6) | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Steps/day | SLHPA | MVHPA | VHPA | Steps/day | SLHPA | MVHPA | VHPA | |||||||||
| r | p-value | r | p-value | r | p-value | r | p-value | r | p-value | r | p-value | r | p-value | r | p-value | |
| A | ||||||||||||||||
| Baseline | ||||||||||||||||
| Body weight | 0.267 | 0.255 | −0.142 | 0.599 | −0.083 | 0.729 | 0.142 | 0.549 | −0.498 | 0.210 | 0.653 | 0.323 | −0.360 | 0.381 | 0.484 | 0.224 |
| BMI | 0.481 | 0.032 | −0.076 | 0.779 | 0.089 | 0.710 | 0.281 | 0.230 | 0.433 | 0.284 | −0.297 | 0.628 | 0.628 | 0.096 | −0.236 | 0.574 |
| ppFEV1 | 0.177 | 0.457 | 0.148 | 0.533 | −0.004 | 0.985 | 0.309 | 0.185 | 0.057 | 0.893 | 0.579 | 0.306 | 0.242 | 0.563 | −0.272 | 0.514 |
| FEV1 z-score | 0.158 | 0.507 | 0.059 | 0.827 | 0.006 | 0.981 | −0.382 | 0.096 | 0.040 | 0.924 | 0.539 | 0.349 | 0.332 | 0.422 | −0.352 | 0.392 |
| Follow-up | ||||||||||||||||
| Body weight | 0.362 | 0.128 | −0.241 | 0.320 | 0.289 | 0.479 | −0.241 | 0.321 | −0.841 | 0.018 | −0.214 | 0.684 | −0.030 | 0.950 | −0.608 | −0.200 |
| BMI | 0.482 | 0.068 | −0.275 | 0.254 | 0.229 | 0.038 | −0.318 | 0.185 | −0.420 | 0.348 | −0.605 | 0.203 | 0.049 | 0.918 | −0.653 | 0.160 |
| ppFEV1 | 0.575 | 0.010 | −0.322 | 0.179 | 0.322 | 0.179 | −0.394 | 0.095 | −0.122 | 0.795 | −0.456 | 0.363 | −0.008 | 0.986 | −0.535 | 0.274 |
| FEV1 z-score | 0.205 | 0.400 | −0.001 | 0.997 | 0.065 | 0.793 | 0.316 | 0.187 | −0.090 | 0.847 | −0.691 | 0.129 | 0.121 | 0.797 | −0.724 | 0.104 |
| B | ||||||||||||||||
| Body weight | 0.333 | 0.163 | 0.118 | 0.674 | 0.376 | 0.113 | −0.135 | 0.581 | 0.234 | 0.614 | −0.455 | 0.545 | −0.001 | 0.998 | −0.032 | 0.952 |
| BMI | 0.312 | 0.194 | 0.064 | 0.820 | 0.401 | 0.089 | −0.102 | 0.678 | 0.130 | 0.780 | −0.480 | 0.520 | −0.128 | 0.785 | 0.039 | 0.941 |
| ppFEV1 | 0.352 | 0.139 | 0.457 | 0.086 | 0.620 | 0.005 | −0.027 | 0.913 | −0.481 | 0.275 | 0.920 | 0.080 | −0.168 | 0.719 | 0.101 | 0.859 |
| FEV1 z-score | −0.040 | 0.871 | 0.077 | 0.785 | 0.487 | 0.035 | −0.007 | 0.976 | −0.323 | 0.480 | 0.936 | 0.037 | 0.078 | 0.868 | −0.022 | 0.967 |
BMI, body mass index; ETI, elexacaftor/tezacaftor/ivacaftor; ppFEV1, percent predicted forced expiratory volume in 1 s; SLPHA, sedentary-to-light habitual physical activity; MVHPA, moderate-to-vigorous habitual physical activity; VVHPA, very vigorous habitual physical activity. Baseline, assessment of habitual physical activity; clinical assessment and testing; Follow-up, clinical assessment and testing between groups. r, Pearson's correlation coefficient.
Bold type indicates a significant result.