Table 2.

Univariate and multivariate analysis of the factor associated with overall mortality of children admitted to PICU, from the time of admission to three months after discharge

		Univariate analysis			Multivariate analysis
Variable		Crude HR	95% CI	P-value	Adjusted HR	95% CI	P-value
Age (Years)
< 1		1.20	0.72–1.67	0.674
1–5		0.95	0.63–1.45	0.820
> 5		Ref
Admiting diagnosis
Infectious		1.65	1.18–2.30	0.004	0.76	0.52–1.12	0.163
Non Infectious		Ref
Type of admission
Medical		2.07	1.37–3.13	0.001
Surgical		Ref
Chronic Illness
Yes		0.93	0.68–1.28	0.669
No		Ref
Organ Dysfunction
Multiple		5.71	3.35–9.73	< 0.001	5.97	3.22– 12.06	< 0.001
Single		2.54	1.44–4.49	0.001	2.77	1.50–5.14	0.001
None		Ref
Creatinine (micromol/L)
Elevated		1.87	1.36–2.58	< 0.001	1.27	0.90–1.78	0.18
Normal		Ref
ALT (units/L)
>114		1.71	1.20–2.43	0.003	0.98	0.67–1.42	0.896
< 114		Ref
Hemoglobin (g/dl)
<11		1.70	1.15–2.50	0.008	1.28	0.85–1.91	0.238
>11		Ref
Platelet (×109/L)
<150		1.21	0.86–1.70	0.271
>450		0.69	0.41–1.16	0.156
150–450		Ref
WBC (×109/L)
<4		1.25	0.45–3.44	0.668
>11		1.29	0.94–1.79	0.120
4–11		Ref

ALT: Alanine aminotransferase, WBC: White blood cells, CI: Confidence interval, HR: Hazard ratio