. 2024 Mar 8;24:193. doi: 10.1186/s12888-023-05297-4

Table 2.

Schedule of assessments for the clinical trial

Domain	Outcome Measurement Instrument	Rater	Follow-up Time Point (Weeks)
Domain	Outcome Measurement Instrument	Rater	0	4	12	24	36	52
Demographics	Locally-developed Demographics Form	Youth	ALL
Diagnosis	K-SADS-PL DSM-5	Evaluator	ALL
Depression Symptom Severity	CDRS-R	Evaluator	ALL	ALL	ALL	ALL	ALL	ALL
Depression Symptom Severity	MFQ	Youth	TAU^a	TAU^a	TAU^a	TAU^a	TAU^a	TAU^a
Depression Diagnosis	DRS	Evaluator	ALL^b		ALL	ALL	ALL	ALL
Overall mental health	CBCL	Caregiver	ALL			ALL		ALL
Function	CADLIS	Youth	TAU^a	TAU^a	TAU^a	TAU^a	TAU^a	TAU^a
Function	CADLIS	Caregiver	ALL
Quality of Life	YQOL-R	Youth	ALL		ALL	ALL	ALL	ALL
Self-Injurious Thoughts and Behaviours	Lifetime C-SSRS	Evaluator	ALL
	Past 6-month C-SSRS	Evaluator	ALL			ALL		ALL
	Lifetime SITBI-NSSI	Evaluator	ALL
	Past 6 month SITBI-NSSI	Evaluator	ALL			ALL		ALL
Global Impression	CGI-Improvement	Clinician				ALL
	PGI-Severity	Youth	TAU^a	TAU^a	TAU^a	TAU^a	TAU^a	TAU^a
	PGI-Improvement	Youth		TAU^a	TAU^a	TAU^a	TAU^a	TAU^a
Anxiety Symptom Severity	RCADS-15-Anx	Youth	TAU^a	TAU^a	TAU^a	TAU^a	TAU^a	TAU^a
Symptoms of Borderline Personality Disorder	CI-BPD	Evaluator	ALL
Hopelessness	BHS	Youth	ALL
Adolescent-Caregiver Conflict	CBQ	Youth	ALL			ALL		ALL
Adolescent-Caregiver Conflict	CBQ	Caregiver	ALL			ALL		ALL
Substance Use	AADIS grid	Youth	ALL
Health Service Use	Past 3 month HSSU	Evaluator	ALL		ALL	ALL	ALL	ALL
Shared Decision-Making	Collaborate	Youth		ALL	ALL	ALL	ALL	ALL
Service Satisfaction	OPOC-MHA	Youth			ALL	ALL	ALL	ALL
CBT Skill Use	CBTSQ	Youth	ALL	ALL	ALL	ALL	ALL	ALL
COVID restrictions	COVID-Impact	Youth	ALL		ALL	ALL	ALL	ALL

K-SADS-PL Kiddie Schedule for Affective Disorders and Schizophrenia- Life-Time Version [58], CDRS-R Childhood Depression Rating Scale -Revised [31], MFQ Mood and Feelings Questionnaire [32], DRS Depression Rating Scale (module within KSADS [58]), CBCL Childhood Behavior Checklist [34], CADLIS-Y Childhood Anxiety and Depression Life Interference Scale - Youth report [33], YQOL-R Youth Quality of Life – Revised [59, 60], C-SSRS Columbia Suicide Severity Rating Scale [46], SITBI-NSSI Self-Injurious Thoughts and Behaviours Interview – Non-Suicidal Self-Injury subsection [61], CGI Clinical Global Impression Scale [44], Patient Global Impression Scale [44], RCADS-15-Anx Revised Children’s Anxiety and Depression Scale – 15 item anxiety subscale [43], CI-BPD Childhood Interview for Borderline Personality Disorder [62], BHS Beck Hopelessness Scale [63], CBQ Conflict Behaviour Questionnaire [64], AADIS Adolescent Alcohol and Drug Involvement Scale [65], HSSU Health System Service Utilization [55], CollaboRATE [66], OPOC-MHA Ontario Perception of Care Tool for Mental Health and Addictions [67], CBTSQ-Cognitive Behavior Therapy Skills Questionnaire [68], COVID-Impact Locally-developed COVID Questionnaire regarding impact of COVID restrictions

^aTo manage respondent burden in CARIBOU-2 pathway arm, these self-report research measures will only be completed by youth in Treatment as Usual arm as the youth in the pathway arm will be completing these measures as part of the measurement-based care package

^bEmbedded in KSADS