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. 2024 Mar 8;22:103. doi: 10.1186/s12916-024-03304-3

Table 4.

Summary of multivariable Cox Regression model to assess the independent association of IgG and IgA against S and N antigens with breakthrough infection

Antibody HR Upper CI Lower CI p-value
IgG S Omicron 0.12 0.50 0.027 0.004
IgA S Omicron 0.48 1.23 0.19 0.13
IgG N Wuhan 0.59 0.93 0.37 0.025
IgA N Wuhan 1.25 2.16 0.72 0.417

Covariates for adjustment included age, comorbidities, chronic medication, sex, smoking, and vaccination with 3 doses (ref: 2 doses), and type of primary vaccination. N = 359

HR hazard ratio