Table 4.
Summary of multivariable Cox Regression model to assess the independent association of IgG and IgA against S and N antigens with breakthrough infection
Antibody | HR | Upper CI | Lower CI | p-value |
---|---|---|---|---|
IgG S Omicron | 0.12 | 0.50 | 0.027 | 0.004 |
IgA S Omicron | 0.48 | 1.23 | 0.19 | 0.13 |
IgG N Wuhan | 0.59 | 0.93 | 0.37 | 0.025 |
IgA N Wuhan | 1.25 | 2.16 | 0.72 | 0.417 |
Covariates for adjustment included age, comorbidities, chronic medication, sex, smoking, and vaccination with 3 doses (ref: 2 doses), and type of primary vaccination. N = 359
HR hazard ratio