Table 2.
Demographic characteristics of RSV positivity children hospitalized with acute lower respiratory tract infection in Hunan, China, July 1, 2013–June 30, 2022
| Characteristics | 2013–2014 No. (%) |
2014–2015 No. (%) |
2015–2016 No. (%) |
2016–2017 No. (%) |
2017–2018 No. (%) |
2018–2019 No. (%) |
2019–2020 No. (%) |
2020–2021 No. (%) |
2021–2022 No. (%) |
Total | χ2/H | P | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. patients | 839 | 797 | 656 | 811 | 831 | 1121 | 596 | 1060 | 855 | 7566 | |||
| Gender, male | 551 (65.7) | 516 (64.7) | 402 (61.3) | 519 (64.0) | 547 (65.8) | 710 (63.3) | 368 (61.7) | 637 (60.1) | 555 (64.9) | 4805 (63.5) | 12.504 | 0.130 | |
| Age, months | 8.0 (4.0, 16.0) | 7.0 (3.0, 14.0) | 7 (3, 15) | 7 (3, 15) | 8 (4, 14) | 8 (3, 16) | 12 (5, 28)a | 14 (7, 29)b | 15 (6, 31)c | 9(4, 20) | 526.252 | <0.001 | |
| Age group, months | 542.017 | <0.001 | |||||||||||
| 1–5 | 295 (35.2) | 336 (42.2) | 264 (40.2) | 372 (45.9) | 301 (36.2) | 424 (37.8) | 168 (28.2) | 215 (20.3) | 181 (21.2) | 2556 (33.8) | |||
| 6–11 | 239 (28.5) | 223 (28.0) | 179 (27.3) | 175 (21.6) | 246 (29.6) | 282 (25.2) | 128 (21.5) | 221 (20.8) | 180 (21.1) | 1873 (24.8) | |||
| 12–23 | 190 (22.6) | 138 (17.3) | 121 (18.4) | 137 (16.9) | 167 (20.1) | 241 (21.5) | 112 (18.8) | 276 (26.0) | 192 (22.5) | 1574 (20.8) | |||
| 24–59 | 114 (13.6) | 95 (11.9) | 87 (13.3) | 120 (14.8) | 113 (13.6) | 165 (14.7) | 180 (30.2) | 334 (31.5) | 283 (33.1) | 1491 (19.7) | |||
| ≥ 60 | 1 (0.1) | 5 (0.6) | 5 (0.8) | 7 (0.9) | 4 (0.5) | 9 (0.8) | 8 (1.3) | 14 (1.3) | 19 (2.2) | 72 (1.0) | |||
| Underlying medical condition | |||||||||||||
| CHD# | 49 (5.8) | 54 (6.8) | 36 (5.5) | 47 (5.8) | 44 (5.3) | 41 (3.7) | 12 (2.0) | 37 (3.5) | 36 (4.2) | 356 (4.7) | 30.048 | <0.001 | |
| Chronic lung diseases* | 4 (0.5) | 2 (0.3) | 4 (0.6) | 4 (0.5) | 3 (0.4) | 2 (0.2) | 2 (0.3) | 4 (0.4) | 3 (0.4) | 28 (0.4) | 3.069 | 0.930 | |
|
Anemia (Hb<90 g/l)† |
16 (1.9) | 12 (1.5) | 12 (1.8) | 12 (1.5) | 7 (0.8) | 16 (1.4) | 2 (0.3) | 12 (1.1) | 8 (0.9) | 97 (1.3) | 11.380 | 0.181 | |
| Malnutrition | 2 (0.2) | 2 (0.3) | 1 (0.2) | 3 (0.4) | 2 (0.2) | 1 (0.1) | 0 (0.0) | 1 (0.1) | 0 (0.0) | 12 (0.2) | 6.331 | 0.610 | |
| Asthma | 26 (3.1) | 15 (1.9) | 16 (2.4) | 16 (2.0) | 20 (2.4) | 36 (3.2) | 23 (3.9) | 36 (3.4) | 32 (3.7) | 220 (2.9) | 12.122 | 0.146 | |
| History of prematurity& | 22 (2.6) | 56 (7.0) | 48 (7.3) | 37 (4.6) | 52 (6.3) | 116 (10.3) | 12 (2.0) | 102 (9.6) | 78 (9.1) | 523 (6.9) | 93.081 | <0.001 | |
| LOS | 7 (6, 9) | 7 (6, 9) | 7 (5, 8) | 6 (5, 8) | 6 (5, 8) | 6 (5, 8) | 6 (5, 7) | 6 (5, 7) | 6 (5, 7) | 6 (5, 8) | 419.400 | <0.001 | |
| hospital costs, $ | 920 (767, 1173) | 1072 (853, 1480) | 1032 (835, 1438) | 967 (794, 1311) | 1094 (853, 1446) | 975 (771, 1382) | 856 (726, 1083) | 1000 (791, 1395) | 1052 (855, 1501) | 992 (799, 1362) | 239.508 | <0.001 | |
| Admission into PICU | 34 (4.1) | 82 (10.3) | 59 (9.0) | 70 (8.6) | 85 (10.2) | 115 (10.3) | 8 (1.3) | 49 (4.6) | 72 (8.4) | 574 (7.6) | 93.330 | <0.001 | |
| Severe pneumonia | 91 (10.8) | 118 (14.8) | 92 (14.0) | 79 (9.7) | 107 (12.9) | 151 (13.5) | 26 (4.4) | 74 (7.0) | 89 (10.4) | 827 (10.9) | 72.214 | <0.001 | |
| Co-infected | 51(6.1) | 68(8.5) | 67(10.2) | 53(6.5) | 79(9.5) | 140(11.3) | 26(4.4) | 18(1.7) | 36(4.2) | 525(6.9) | 118.205 | <0.001 | |
Notes: The data of age, months, LOS, and hospital costs were presented with a median (P25, P75). No. (%), which stands for patient number (percentage). LOS means length of stay. PICU means pediatric intensive care unit. $ means US dollar. &Prematurity was defined as birth at gestational age < 37 weeks. #CHD, Congenital heart disease. *For example, bronchopulmonary dysplasia. †Moderate to severe anemia, defined as hemoglobin < 90 g/L at hospital admission. aP < 0.05, for comparison of median age in 2019–2020 with other groups; bP < 0.05, for comparison of median age in 2020–2021 with other groups; cP < 0.05, for comparison of median age in 2021–2022 with other groups (exclude 2020–2021)