Table 2a.
Univariate/multivariate analysis assessing association between demographic/clinical characteristics and severe RSV-disease. Policlinico-Foggia-Hospital, Apulia region, Italy, 2011 − 2020
| Very severe RSV disease* | Univariate Analysis | Multivariate Analysis | ||||||
|---|---|---|---|---|---|---|---|---|
| Yes (N = 208) | No (N = 624) | |||||||
| Characteristics | n (%)/mean (SD) | n (%)/mean (SD) | OR | 95% CI | p value | OR | 95% CI | p value |
| Sex, n (%) | ||||||||
| Male | 119 (57.2) | 351 (56.2) | Ref. | |||||
| Female | 89 (42.8) | 273 (43.8) | 1.03 | 0.75–1.45 | 0.8086 | |||
| Age group (months), mean (SD) | 1.8 (8.7) | 10.9 (14.7) | 0.0000 | 14.8 | 8.30–26.31 | 0.000** | ||
| LOS (days), mean (SD) | 10.02 (17.47) | 5.59 (14.87) | 0.0002 | 1.01 | 1.0–1.02 | 0.030*** | ||
| RSV subtype, n (%) | ||||||||
| A | 116 (55.8) | 358 (57.4) | - | - | Ref. | |||
| B | 92 (44.2) | 266 (42.6) | 0.94 | 0.67–1.30 | 0.6860 | |||
| Delivery during the RSV infection season | 182 (87.5) | 350 (56.1) | 5.5 | 3.49–8.86 | 0.0000 | 1.4 | 0.82–2.53 | 0.192 |
| Comorbid condition | ||||||||
| Pediatric CCCs | 51 (24.5) | 74 (11.9) | 2.4 | 1.58–3.65 | 0.0000 | 1.0 | 0.42–2.44 | 0.957 |
| History of prematurity | 41 (19.7) | 29 (4.6) | 5.0 | 2.9–8.6 | 0.0000 | 4.4 | 1.57–12.11 | 0.005 |
CCCs: complex chronic conditions; CI: confidence interval; LOS: length of stay; RSV: respiratory syncytial virus; SD: standard deviation
*Al least one condition: neonatal intensive care unit admission, mechanical ventilation, respiratory therapy, extracorporeal membrane oxygenation, death
**Age 0–2 months vs. >2 months
***LOS included in the model as days