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. 2024 Mar 7;21:25. doi: 10.1186/s12987-024-00520-0

Table 2.

Quantitative results of the breathing effects on four parameters of CSF at extracranial (C2-C3) and intracranial (aqueduct) planes

C2-C3 (n = 25)
Mean value Δp Δp% Φp° Δp% without Φp° p value
Qnet (ml/min) 9.4 ± 5.6 20 ± 9.9 6.3 ± 3.1 33 ± 27 5.3 ± 2.8 **
Amplitude (ml/min) 338 ± 82 22 ± 9 6.8 ± 2.8 -11 ± 75 2.2 ± 3.7 **
SV (mm3) 608 ± 160 85 ± 56 14 ± 7.1 -36 ± 43 8.7 ± 6.4 **
Tc (ms) 832 ± 164 49 ± 28 6.0 ± 3.4 -64 ± 51 2.5 ± 3.4 **
Aqueduct ( n  = 20)
Mean value Δp Δp% Φp° Δp% without Φp° p value
Qnet (ml/min) -0.34 ± 0.93 2.8 ± 1.7 11 ± 6.8 58 ± 36 6.5 ± 5.7 **
Amplitude (ml/min) 26 ± 12 2.9 ± 1.8 11 ± 4.9 -80 ± 82 -1.6 ± 8.8 0.36
SV (mm3) 55 ± 34 9.0 ± 7.5 15 ± 5 -42 ± 60 1.9 ± 9.4 0.43
Tc (ms) 837 ± 154 51 ± 32 5.8 ± 3.4 -40 ± 47 3.4 ± 3.2 **

Δp indicates the difference between the inspiratory and expiratory phases of the corresponding parameter-p, Δp% is the percentage expression. Δp% without Φp° indicates the Δp% without taking into account the phase shift (Φp° = 0). The statistical significance (p-value) of Δp% without Φp° compared to zero is tested with t-test (* = p < 0.05; ** = p < 0.01)