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Differences between the structure of full-length CPE and ΔN37CPE (A) at the N-terminus, the N-terminal domain of full-length CPE is shown in maroon that for ΔN37CPE in pale green. (B) P191 peptide-flip. The full-length CPE conformation is shown in maroon, and symmetry related molecules in the ΔN37CPE crystal packing in semi-transparent grey. It is evident that the full-length conformation clashes with these residues. The ΔN37CPE is in pale green, red and cyan and does not clash.
