Table 5.
Performance of the model for glaucoma diagnosis in terms of AUC, Sensitivity, and Specificity, based on different genders, ages, races, glaucoma severity levels, and IOP. P-values were calculated based on the GEE model. The significance level is < 0.05
| Characteristics | AUC (95% CI) | Sensitivity | Specificity | GEE P-value |
|---|---|---|---|---|
| Gender | 0.46 | |||
| Female | 0.96 (0.94–0.98) | 0.94 (0.92–0.96) | 0.86 (0.84–0.89) | |
| Male | 0.95 (0.93–0.98) | 0.93 (0.91–0.96) | 0.85 (0.83–0.88) | |
| Age | 0.41 | |||
| < 55 years | 0.95 (0.92–0.97) | 0.93 (0.90–0.96) | 0.86 (0.83–0.90) | |
| ≥ 55 years | 0.96 (0.94–0.98) | 0.95 (0.93–0.97) | 0.87 (0.85–0.90) | |
| Race | 0.44 | |||
| Non African-American | 0.95 (0.92–0.97) | 0.93 (0.90–0.96) | 0.85 (0.82–0.88) | |
| African-American | 0.96 (0.93–0.98) | 0.94 (0.90–0.97) | 0.87 (0.84–0.90) | |
| Mean deviation (MD) | ||||
| ≥ 0 dB | 0.94 (0.91–0.96) | 0.89 (0.85–0.93) | 0.82 (0.78–0.86) | mild vs early:0.48 |
| −4 dB ≤ & < 0 dB | 0.95 (0.92–0.97) | 0.92 (0.89–0.95) | 0.84 (0.81–0.87) | moderate vs early: 0.27 |
| −8 dB ≤ & < −4 dB | 0.95 (0.93–0.97) | 0.93 (0.90–0.96) | 0.85 (0.83–0.88) | |
| ≤ −8 dB | 0.97 (0.94–0.99) | 0.95 (0.93–0.98) | 0.87 (0.85–0.90) | advanced vs early: 0.04 |
| Intraocular pressure (IOP) | 0.38 | |||
| < 21 mmHg | 0.95 (0.92–0.97) | 0.91 (0.89–0.94) | 0.85 (0.82–0.88) | |
| ≥ 21 mmHg | 0.96 (0.93–0.99) | 0.93 (0.90–0.96) | 0.88 (0.85–0.90) |