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. Author manuscript; available in PMC: 2025 Jun 1.
Published in final edited form as: Biomed Signal Process Control. 2024 Feb 14;92:106061. doi: 10.1016/j.bspc.2024.106061

Table 5.

Performance of the model for glaucoma diagnosis in terms of AUC, Sensitivity, and Specificity, based on different genders, ages, races, glaucoma severity levels, and IOP. P-values were calculated based on the GEE model. The significance level is < 0.05

Characteristics AUC (95% CI) Sensitivity Specificity GEE P-value
Gender 0.46
 Female 0.96 (0.94–0.98) 0.94 (0.92–0.96) 0.86 (0.84–0.89)
 Male 0.95 (0.93–0.98) 0.93 (0.91–0.96) 0.85 (0.83–0.88)
Age 0.41
 < 55 years 0.95 (0.92–0.97) 0.93 (0.90–0.96) 0.86 (0.83–0.90)
 ≥ 55 years 0.96 (0.94–0.98) 0.95 (0.93–0.97) 0.87 (0.85–0.90)
Race 0.44
 Non African-American 0.95 (0.92–0.97) 0.93 (0.90–0.96) 0.85 (0.82–0.88)
 African-American 0.96 (0.93–0.98) 0.94 (0.90–0.97) 0.87 (0.84–0.90)
Mean deviation (MD)
 ≥ 0 dB 0.94 (0.91–0.96) 0.89 (0.85–0.93) 0.82 (0.78–0.86) mild vs early:0.48
 −4 dB ≤ & < 0 dB 0.95 (0.92–0.97) 0.92 (0.89–0.95) 0.84 (0.81–0.87) moderate vs early: 0.27
 −8 dB ≤ & < −4 dB 0.95 (0.93–0.97) 0.93 (0.90–0.96) 0.85 (0.83–0.88)
 ≤ −8 dB 0.97 (0.94–0.99) 0.95 (0.93–0.98) 0.87 (0.85–0.90) advanced vs early: 0.04
Intraocular pressure (IOP) 0.38
 < 21 mmHg 0.95 (0.92–0.97) 0.91 (0.89–0.94) 0.85 (0.82–0.88)
 ≥ 21 mmHg 0.96 (0.93–0.99) 0.93 (0.90–0.96) 0.88 (0.85–0.90)