Table 5.
Performance of the model for glaucoma diagnosis in terms of AUC, Sensitivity, and Specificity, based on different genders, ages, races, glaucoma severity levels, and IOP. P-values were calculated based on the GEE model. The significance level is < 0.05
Characteristics | AUC (95% CI) | Sensitivity | Specificity | GEE P-value |
---|---|---|---|---|
Gender | 0.46 | |||
Female | 0.96 (0.94–0.98) | 0.94 (0.92–0.96) | 0.86 (0.84–0.89) | |
Male | 0.95 (0.93–0.98) | 0.93 (0.91–0.96) | 0.85 (0.83–0.88) | |
Age | 0.41 | |||
< 55 years | 0.95 (0.92–0.97) | 0.93 (0.90–0.96) | 0.86 (0.83–0.90) | |
≥ 55 years | 0.96 (0.94–0.98) | 0.95 (0.93–0.97) | 0.87 (0.85–0.90) | |
Race | 0.44 | |||
Non African-American | 0.95 (0.92–0.97) | 0.93 (0.90–0.96) | 0.85 (0.82–0.88) | |
African-American | 0.96 (0.93–0.98) | 0.94 (0.90–0.97) | 0.87 (0.84–0.90) | |
Mean deviation (MD) | ||||
≥ 0 dB | 0.94 (0.91–0.96) | 0.89 (0.85–0.93) | 0.82 (0.78–0.86) | mild vs early:0.48 |
−4 dB ≤ & < 0 dB | 0.95 (0.92–0.97) | 0.92 (0.89–0.95) | 0.84 (0.81–0.87) | moderate vs early: 0.27 |
−8 dB ≤ & < −4 dB | 0.95 (0.93–0.97) | 0.93 (0.90–0.96) | 0.85 (0.83–0.88) | |
≤ −8 dB | 0.97 (0.94–0.99) | 0.95 (0.93–0.98) | 0.87 (0.85–0.90) | advanced vs early: 0.04 |
Intraocular pressure (IOP) | 0.38 | |||
< 21 mmHg | 0.95 (0.92–0.97) | 0.91 (0.89–0.94) | 0.85 (0.82–0.88) | |
≥ 21 mmHg | 0.96 (0.93–0.99) | 0.93 (0.90–0.96) | 0.88 (0.85–0.90) |