Table 3.
Prevalence and correlates of perceptions of knowledge of clinical trials by demographics, health status, and health communication behaviors
| Prevalencea | Prevalence | ORb | AORc | Prevalence | ORd | AORe | |||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| Correlates | Don’t know anything | Know a little | Know a little compared to Don’t know | Know a little compared to Don’t know | Know a lot | Know a lot compared to Don’t know | Know a lot compared to Don’t know | ||
|
| |||||||||
| % (95% CI) | % (95% CI) | Unadjusted OR (95% CI) | Adjusted OR (95% CI) | % (95% CI) | Unadjusted OR (95% CI) | Adjusted OR (95% CI) | |||
|
| |||||||||
| Entire Sample | 41.3 (38.7, 44.0) | 49.3 (46.8, 51.8) | -- | -- | 9.4 (7.9, 11.1) | -- | -- | ||
| Demographics | |||||||||
| Gender | |||||||||
| Male | 41.9 (37.6, 46.3) | 48.7 (44.7, 52.7) | Ref | Ref | 9.5 (7.2, 12.4) | Ref | Ref | ||
| Female | 39.8 (36.2, 43.5) | 50.7 (47.3, 54.1) | 1.10 (0.86, 1.40) | 0.99 (0.74, 1.34) | 9.5 (7.8, 11.4) | 1.05 (0.71, 1.56) | 1.20 (0.77, 1.88) | ||
| Race/Ethnicity | |||||||||
| Non-Hispanic White | 36.7 (33.5, 40.1) | 52.8 (49.6, 56.1) | Ref | Ref | 10.4 (8.4, 12.9) | Ref | Ref | ||
| Non-Hispanic Black | 40.8 (33.6, 48.4) | 51.9 (44.5, 59.2) | 0.88 (0.63, 1.25) | 0.94 (0.58, 1.52) | 7.3 (4.6, 11.5) | 0.63 (0.35, 1.14) | 0.88 (0.41, 1.91) | ||
| Hispanic | 51.9 (43.8, 59.9) | 40.4 (33.3, 48.0) | 0.54** (0.37, 0.79) | 0.63 (0.39, 1.03) | 7.7 (4.5, 12.7) | 0.52* (0.27, 1.00) | 0.78 (0.37, 1.64) | ||
| Non-Hispanic Asian | 49.7 (38.3, 61.2) | 36.8 (27.6, 47.1) | 0.52** (0.33, 0.82) | 0.43*** (0.26, 0.70) | 13.4 (7.5, 23.0) | 0.95 (0.45, 2.04) | 0.56 (0.25, 1.25) | ||
| Non-Hispanic Other | 41.1 (28.2, 55.4) | 53.0 (39.3, 66.3) | 0.90 (0.48, 1.68) | 0.98 (0.48, 2.00) | 5.9 (3.3, 10.4) | 0.50 (0.24, 1.07) | 0.47 (0.16, 1.37) | ||
| Age | |||||||||
| 18–34 | 42.9 (36.2, 49.9) | 46.2 (40.1, 52.4) | Ref | Ref | 10.9 (7.5, 15.6) | Ref | Ref | ||
| 35–49 | 37.2 (31.6, 43.2) | 51.9 (45.8, 58.1) | 1.30 (0.86, 1.96) | 1.27 (0.82, 1.97) | 10.8 (7.5, 15.3) | 1.14 (0.63, 2.07) | 1.11 (0.59, 2.08) | ||
| 50–64 | 39.7 (35.6, 44.0) | 52.9 (48.7, 57.0) | 1.24 (0.90, 1.69) | 1.32 (0.93, 1.89) | 7.4 (5.9, 9.3) | 0.73 (0.42, 1.29) | 0.90 (0.51, 1.59) | ||
| 65–74 | 35.7 (30.7, 41.0) | 56.2 (50.7, 61.6) | 1.46 (0.99, 2.16) | 1.99** (1.30, 3.04) | 8.1 (6.0, 10.9) | 0.89 (0.49, 1.64) | 1.64 (0.84, 3.22) | ||
| 75+ | 56.1 (49.4, 62.6) | 37.2 (31.6, 43.1) | 0.62* (0.43, 0.89) | 0.84 (0.44, 1.57) | 6.7 (4.3, 10.2) | 0.47* (0.25, 0.89) | 0.82 (0.28, 2.39) | ||
| Education | |||||||||
| Less than HS | 68.2 (58.2, 76.7) | 29.7 (21.3, 39.6) | Ref | Ref | 2.2 (1.2, 3.9) | Ref | Ref | ||
| HS Grad | 53.6 (48.0, 59.1) | 44.1 (38.7, 49.7) | 1.89* (1.16, 3.08) | 1.79 (0.84, 3.85) | 2.3 (1.4, 3.8) | 1.35 (0.63, 2.88) | 0.99 (0.35, 2.80) | ||
| Some College | 41.9 (37.6, 46.3) | 51.7 (47.1, 56.2) | 2.84*** (1.78, 4.51) | 2.09 (0.97, 4.48) | 6.5 (4.3, 9.7) | 4.88*** (2.26, 10.52) | 2.45 (0.85, 7.02) | ||
| Bachelor’s Degree or Higher | 23.9 (20.1, 28.1) | 56.0 (51.9, 59.9) | 5.39*** (3.22, 9.01) | 4.09** (1.79, 9.37) | 20.2 (16.7, 24.2) | 26.68*** (13.00, 54.76) | 16.10*** (5.84, 44.40) | ||
| Income | |||||||||
| < $20,000 | 49.8 (42.4, 57.1) | 41.4 34.4, 48.8) | Ref | Ref | 8.8 (5.6, 13.5) | Ref | Ref | ||
| $20,000–35,000 | 43.3 (35.7, 51.2) | 50.6 (42.8, 58.3) | 1.40 (0.88, 2.23) | 1.35 (0.68, 2.67) | 6.1 (3.2, 11.5) | 0.80 (0.37, 1.76) | 0.66 (0.25, 1.80) | ||
| $35,000–50,000 | 50.1 (42.5, 57.7) | 41.8 (34.9, 49.0) | 1.00 (0.63, 1.61) | 0.80 (0.42, 1.52) | 8.1 (5.1, 12.8) | 0.92 (0.43, 1.96) | 0.52 (0.20, 1.29) | ||
| $50,000–75,000 | 38.8 (33.2, 44.7) | 54.5 (49.0, 59.9) | 1.69* (1.12, 2.55) | 1.36 (0.79, 2.34) | 6.7 (4.3, 10.3) | 0.98 (0.48, 2.00) | 0.58 (0.24, 1.37) | ||
| $75,000+ | 35.6 (31.5, 40.0) | 52.1 (48.0, 56.2) | 1.76** (1.25, 2.47) | 1.02 (0.61, 1.73) | 12.3 (9.6, 15.6) | 1.95* (1.05, 3.63) | 0.62 (0.29, 1.32) | ||
| Urban-Rural | |||||||||
| Small town/rural | 40.7 (30.5, 51.8) | 53.1 (42.2, 63.7) | Ref | Ref | 6.2 (2.4, 14.9) | Ref | Ref | ||
| Micropolitan | 51.3 (40.3, 62.1) | 40.0 (30.0, 50.9) | 0.60 (0.32, 1.12) | 0.47 (0.20, 1.09) | 8.8 (4.3, 17.1) | 1.13 (0.31, 4.13) | 0.96 (0.23, 4.0) | ||
| Metropolitan | 40.4 (37.5, 43.5) | 49.9 (47.2, 52.6) | 0.95 (0.58, 1.55) | 0.67 (0.34, 1.33) | 9.6 (8.0, 11.5) | 1.57 (0.57, 4.36) | 1.35 (0.39, 4.64) | ||
| Cancer History | |||||||||
| No | 41.6 (38.8, 44.5) | 49.1 (46.5, 51.8) | Ref | Ref | 9.2 (7.6, 11.1) | Ref | Ref | ||
| Yes | 36.2 (30.1, 42.7) | 54.4 (48.3, 60.3) | 1.27 (0.94, 1.72) | 1.34 (0.84, 2.13) | 9.5 (7.2, 12.4) | 1.18 (0.77, 1.81) | 1.31 (0.74, 2.29) | ||
| Discuss with Healthcare Providers | |||||||||
| Emailed to communicate with healthcare providers | |||||||||
| No | 51.7 (48.0, 55.4) | 43.1 (39.4, 46.9) | Ref | Ref | 5.2 (4.2, 6.4) | Ref | Ref | ||
| Yes | 29.1 (25.4, 33.2) | 56.9 (53.0, 60.8) | 2.34*** (1.81, 3.04) | 1.66** (1.18, 2.34) | 14.0 (11.4, 17.0) | 4.77*** (3.49, 6.52) | 2.47*** (1.55, 3.92) | ||
| Used a tablet or smartphone to help with discussions with health care provider | |||||||||
| No | 44.6 (40.8, 48.4) | 47.5 (43.8, 51.2) | Ref | Ref | 7.9 (6.1, 10.2) | Ref | Ref | ||
| Yes | 30.1 (25.7, 34.8) | 56.3 (51.5, 61.0) | 1.76*** (1.32, 2.34) | 1.19 (0.81, 1.75) | 13.6 (10.8, 17.1) | 2.55*** (1.68, 3.87) | 1.06 (0.58, 1.92) | ||
| Seek Health Information | |||||||||
| Use Internet to look for health-related information | |||||||||
| No | 57.2 (52.2, 62.0) | 39.2 (34.5, 44.2) | Ref | Ref | 3.6 (2.6, 4.9) | Ref | Ref | ||
| Yes | 35.3 (32.2, 38.5) | 53.2 (50.2, 56.2) | 2.20*** (1.71, 2.83) | 1.16 (0.81, 1.67) | 11.5 (9.6, 13.8) | 5.19*** (3.43, 7.85) | 1.60 (0.89, 2.89) | ||
| Used tablet or smartphone to make decisions about health | |||||||||
| No | 40.0 (35.9, 44.3) | 51.3 (47.4, 55.1) | Ref | Ref | 8.7 (6.8, 11.0) | Ref | Ref | ||
| Yes | 37.2 (32.4, 42.1) | 50.6 (46.2, 55.0) | 1.06 (0.80, 1.42) | 0.69 (0.47, 1.01) | 12.2 (9.6, 15.5) | 1.52 (0.98, 2.35) | 0.89 (0.54, 1.47) | ||
| Visited a social networking site e.g., Facebook | |||||||||
| No | 52.1 (47.3, 56.9) | 41.5 (37.1, 46.1) | Ref | Ref | 6.4 (4.4, 9.0) | Ref | Ref | ||
| Yes | 37.3 (34.0, 40.8) | 52.3 (49.3, 55.3) | 1.76*** (1.37, 2.26) | 1.28 (0.83, 1.95) | 10.3 (8.3, 12.7) | 2.27** (1.35, 3.80) | 1.17 (0.59, 2.34) | ||
| Watch health-related videos on Youtube | |||||||||
| No | 46.6 (43.1, 50.1) | 47.1 (43.7, 50.6) | Ref | Ref | 6.3 (5.1, 7.7) | Ref | Ref | ||
| Yes | 32.6 (28.5, 37.1) | 53.6 (48.9, 58.2) | 1.62*** (1.24, 2.12) | 1.24 (0.85, 1.81) | 13.8 (11.0, 17.1) | 3.15*** (2.27, 4.37) | 1.90** (1.22, 2.97) | ||
| Share Information | |||||||||
| Use social network to share health-related info | |||||||||
| No | 43.3 (40.3, 46.3) | 48.0 (45.2, 50.9) | Ref | Ref | 8.7 (7.2, 11.1) | Ref | Ref | ||
| Yes | 26.6 (21.3, 32.7) | 60.0 (53.1, 66.4) | 2.03*** (1.44, 2.87) | 1.40 (0.92, 2.14) | 13.4 (9.7, 18.4) | 2.53*** (1.68, 3.80) | 1.19 (0.70, 2.01) | ||
| Use health-related online forum or support group | |||||||||
| No | 43.5 (40.7, 46.4) | 47.9 (45.2, 50.6) | Ref | Ref | 8.6 (7.3, 10.0) | Ref | Ref | ||
| Yes | 17.8 (12.6 24.4) | 65.5 (56.8, 73.4) | 3.35*** (2.16, 5.21) | 2.21*** (1.41, 3.46) | 16.7 (10.5, 25.5) | 4.78*** (2.59, 8.83) | 2.56** (1.31, 5.00) | ||
a
prevalence estimates of percentages (with 95% confidence intervals) generated by cross-classification of response option levels of each correlate by levels of clinical trial knowledge
b
odds ratios (unadjusted) from logistic regression models testing differences in correlate response options by level of clinical trial knowledge (for this column, comparing “Know a little” to “Don’t know anything” (reference))
c
adjusted odds ratio estimates from a single logistic regression model testing differences in correlate response options by levels of clinical trial knowledge (for this column, comparing “Know a little” to “Don’t know anything” (reference))
d
odds ratios (unadjusted) from logistic regression models testing differences in correlate response options by levels of clinical trial knowledge (for this column, comparing “Know a lot” to “Don’t know anything” (reference))
e
adjusted odds ratio estimates from a single logistic regression model testing differences in correlate response options by levels of clinical trial knowledge (for this column, comparing “Know a lot” to “Don’t know anything” (reference))