Figure 1. Validation of SPLC-RAT for predicting a 10-year SPLC risk among ever-smoking lung cancer patients in the Mayo Clinic cohort (N=8,448).
(A) Calibration plots with discriminative performance (area under the receiver operative characteristics curve; AUC) and prediction accuracy (Brier score). (B) Plots of mean difference between predicted and observed probability (calibration error) across risk deciles. All estimates were based on the pooled prediction from 10 multiply imputed datasets (N=8448×10) using Rubin’s rules.
Abbreviations: SPLC, second primary lung cancer; SPLC-RAT, second primary lung cancer-risk assessment tool.