Table 2:

Baseline characteristics of patients with and without BE on follow-up EGD after negative initial EGD.

	GIQuIC				TriNetX
Characteristics	Total N= 214,318	No BE N = 210,591	BE present N = 3,727	p-value	Total N=153,445	No BE N =148,123	BE present N = 5,322	p- value
Age (years)				<0.01				<0.01
<50	47,643 (22.2%)	47,029 (22.3%)	614 (16.5%)		45,479 (30.7%)	44,248 (31.0%)	1,231 (24.0%)
50-80	151,896 (70.9%)	148,953 (70.7%)	2,943 (79.0%)		96,001 (64.8%)	92,256 (64.5%)	3,745 (73.1%)
>80	14,779 (6.9%)	14,609 (6.9%)	170 (4.6%)		6,592 (4.5%)	6,445 (4.5%)	147 (2.9%)
Male sex	83,903 (39.1%)	81,909 (38.9%)	1,994 (53.5%)	<0.01	61,269 (39.9%)	58,572 (39.5%)	2,697 (50.7%)	<0.01
White race *	145,918 (82.2%)	143,211 (82.1%)	2,707 (89.8%)	<0.01	109,018 (71.0%)	104,751 (70.7%)	4,267 (80.2%)	<0.01
GERD symptoms	75,281 (35.1%)	73,085 (34.7%)	2,196 (58.9%)	<0.01	119,213 (77.7%)	114,456 (77.3%)	4,757 (89.4%)	<0.01
Smoking (ever)	N/A	N/A	N/A		26,821 (17.5%)	26,073 (17.6%)	748 (14.1%)	<0.01
Obesity (BMI > 30)	13,804 (36.0%)	13,421 (35.9%)	383 (37.4%)	0.31	26,963 (38.9%)	25,989 (38.8%)	974 (40.3%)	0.16
Time interval between initial negative EGD and subsequent EGD				<0.01				<0.01
<1 year	104,366 (48.7%)	102,284 (48.6%)	2,082 (55.9%)		72,793 (47.4%)	70,603 (47.7%)	2,190 (41.1%)
1-3 years	73,034 (34.1%)	71,922 (34.2%)	1,112 (29.8%)		41,542 (27.1%)	39,845 (26.9%)	1,697 (31.9%)
3-5 years	29,387 (13.7%)	28,954 (13.7%)	433 (11.6%)		19,416 (12.7%)	18,726 (12.6%)	690 (13.0%)
≥ 5 years	7,531 (3.5%)	7,431 (3.5%)	100 (2.7%)		19,694 (12.8%)	18,949 (12.8%)	745 (14.0%)
High risk population (GERD + ≥1 risk factor)	73,831 (34.4%)	71,655 (34.0%)	2,176 (58.4%)	<0.01	116,423 (75.9%)	111,710 (75.4%)	4,713 (88.6%)	<0.01

^*Selection of white race could be accompanied with selection of 1 or more other races, and/or Hispanic ethnicity.