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. Author manuscript; available in PMC: 2025 Mar 1.
Published in final edited form as: Clin Gastroenterol Hepatol. 2023 Sep 15;22(3):523–531.e3. doi: 10.1016/j.cgh.2023.08.035

Table 3:

Predictors for BE on follow-up EGD after negative initial EGD for BE.

Characteristics GIQuIC TriNetX
Multivariate OR
(95% CI)
p-value Multivariate OR
(95% CI)
p-value
Age
<50 REF REF
50-80 1.65 (1.51-1.80) <0.01 1.41 (1.28-1.56) <0.01
>80 1.17 (0.98-1.39) 0.077 0.85 (0.66-1.10) 0.2
Sex
Female REF REF
Male 1.89 (1.68-1.92) <0.01 1.73 (1.59-1.88) <0.01
Race
Other REF REF
White 1.86 (1.65-2.10) <0.01 1.68 (1.51-1.89) <0.01
Smoking history
No NA REF
Yes 0.71 (0.63-0.80) <0.01
GERD
No REF REF
Yes <0.01 2.23 (1.93-2.59) <0.01
Hiatal Hernia
No NA REF
Yes NA 1.07 (0.97-1.12) <0.01
Obesity (BMI > 30)
No REF REF
Yes 1.06 (0.93-1.21) NS 1.03 (0.95, 1.12) 0.5
Time between EGD1 and EGD2
<1 year 1.59 (1.47-1.71) <0.01 REF
1-3 years REF 1.34 (1.20, 1.49) <0.01
3-5 years 0.89 (0.80-1.00) 0.04 1.29 (1.13, 1.46) <0.01
>5 years 0.80 (0.65-0.99) 0.03 1.41 (1.25, 1.58) <0 .01
Proceduralist NA NA
Gastroenterologist REF
Non-gastroenterologist 1.10 (0.97-1.25) 0.14