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. Author manuscript; available in PMC: 2025 Feb 19.
Published in final edited form as: Chem Res Toxicol. 2024 Jan 9;37(2):340–360. doi: 10.1021/acs.chemrestox.3c00333

Figure 10.

Figure 10.

DNA adduct levels in kidneys and liver of rats treated with a 13-carcinogen mixture 24 h following dosing. [13C10]-dG-C8–4-ABP was employed to estimate levels of dG-N2-N4-4-ABP and dA-C8–4-ABP; [13C10]-dG-C8-AαC was used to estimate dG-C8-MeAαC and dG-C8-AF; [15N5]-dA-N6-AL-I was employed to estimate dA-N6-AL-III and dA-3-ABA isomers, and [15N5]-dG-N2-AL-I was used to estimate dG-3-ABA isomers. The statistical significance between adduct levels formed in the kidney and liver was done with Welch’s unpaired t-test using Prism 8.4.3 (GraphPad Software, La Jolla, CA). (*P < 0.05; **P < 0.01, ***P < 0.001, ****P < 0.0001)