Figure 8.

Wide-SIM/MS2 and wSIM-City EICs of 4-ABP, HAA, B[a]P DNA adducts in kidney DNA of untreated and treated rats given a 13-carcinogen mixture 24 h following dosing The precursor ions are shown in black, and the aglycone ions are depicted in red. The EICs identified by wSIM-City are plotted for dG-C8–4-ABP, dG-C8-AαC, dG-C8-PhIP, dG-N2-B[a]P, and their aglycone m/z peak intensities within 5 ppm mass tolerance.