Chromoanagenesis
	Chromothripsis	Chromoplexy	Chromoanasynthesis
Origin	‘chromo’ for chromosomes and ‘thripsis’ for shattering into pieces	‘chromo’ for chromosomes and ‘pleko’ for braid or weave together	‘chromo’ for chromosomes and ‘anasynthesis’ for reconstitution
Definition	A single event of local chromosome shattering that produces tens to hundreds of fragments, followed by random restitching driven by NHEJ	Co-occurrence of multiple inter- and intra-chromosomal translocations and (to a lesser extent) deletions, frequently involving five or more chromosomes	A replication-based process with local rearrangements and altered gene copy numbers due to serial fork stalling or template switching, or microhomology-mediated break-induced replication
Single event	Yes	?	Yes
Chromosomes	1–2	≥5	1–2
Deletions	Yes	Yes	Yes
Duplications	Rare	Rare	Frequent
Translocations	Yes	Yes	Yes
Frequency in cancer a	40–60%	10%	5%

^aInferred from Ref ³³.