Table III.
Age (mean, years [95%Confidence Interval, CI]) of first recorded diagnosis of Atopic Dermatitis (AD) and other allergic illness (OAI) and timing of onset of AD relative to OAI in the overall cohort, children of mothers with AD and children of mothers without AD
Overall Cohort | Children of Mothers without AD | Children of Mothers with AD | |
---|---|---|---|
N (%) | 1,224,243 (100) | 913,693 (74.63) | 310,550 (25.37) |
Age first recorded diagnosis Atopic Dermatitis | |||
years (95%CI) | 3.32 (3.30, 3.34) | 3.42 (3.40, 3.44) | 2.98 (2.95, 3.02) |
Age first recorded diagnosis Asthma | |||
years (95%CI) | 5.52 (5.49, 5.54) | 5.60(5.57,5.63) | 5.18(5.13,5.24) |
Age first AD recorded diagnosis seasonal allergies | |||
years (95%CI) | 9.14(9.11,9.18) | 9.33(9.29,9.37) | 8.49(8.42,8.56) |
Age first AD recorded diagnosis food allergies | |||
years (95%CI) | 4.48 (4.39,4.58) | 4.51(4.40,4.61) | 4.40(4.21,4.59) |
Age at 1st recorded diagnosis of AD, years (range) if mother had OAI a | |||
No OAI | 3.46(3.44,3.48) | 3.54(3.52,3.57) | 3.07(3.03,3.12) |
One OAI | 3.03(3.00,3.06) | 3.09(3.05,3.12) | 2.90(2.84,2.96) |
Two OAI | 2.93(2.87,2.99) | 3.02(2.94,3.10) | 2.81(2.72,2.89) |
Three OAI | 2.38(2.00,2.77) | 2.56(2.03,3.09) | 2.09(1.57,2.62) |
Age at first AD recorded diagnosis relative to OAI | |||
AD preceding asthma | 2.92(2.91,2.94) | 3.01(3.00,3.04) | 2.60(2.57,2.63) |
AD preceding seasonal allergies | 3.05(3.04,3.07) | 3.15(3.13,3.17) | 2.70(2.67,2.73) |
AD preceding food allergies | 3.36(3.25,3.28) | 3.678(3.45,3.39) | 2.91(2.88,2.94) |
AD occurring after asthma | 8.40(8.31,8.49) | 8.64(8.54,8.75) | 7.61(7.44,7.78) |
AD occurring after seasonal allergies | 10.99(10.84,10.15) | 11.30(11.11,11.48) | 10.109.83,10.37) |
AD occurring after food allergies | 6.78(6.51,7.05) | 6.59(6.27,6.90) | 7.36(6.83,7.89) |
maternal history of asthma, seasonal allergy and/or food allergy