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. Author manuscript; available in PMC: 2025 Mar 1.
Published in final edited form as: J Am Acad Dermatol. 2023 Nov 18;90(3):561–568. doi: 10.1016/j.jaad.2023.11.013

Table III.

Age (mean, years [95%Confidence Interval, CI]) of first recorded diagnosis of Atopic Dermatitis (AD) and other allergic illness (OAI) and timing of onset of AD relative to OAI in the overall cohort, children of mothers with AD and children of mothers without AD

Overall Cohort Children of Mothers without AD Children of Mothers with AD
N (%) 1,224,243 (100) 913,693 (74.63) 310,550 (25.37)
Age first recorded diagnosis Atopic Dermatitis
years (95%CI) 3.32 (3.30, 3.34) 3.42 (3.40, 3.44) 2.98 (2.95, 3.02)
Age first recorded diagnosis Asthma
years (95%CI) 5.52 (5.49, 5.54) 5.60(5.57,5.63) 5.18(5.13,5.24)
Age first AD recorded diagnosis seasonal allergies
years (95%CI) 9.14(9.11,9.18) 9.33(9.29,9.37) 8.49(8.42,8.56)
Age first AD recorded diagnosis food allergies
years (95%CI) 4.48 (4.39,4.58) 4.51(4.40,4.61) 4.40(4.21,4.59)
Age at 1st recorded diagnosis of AD, years (range) if mother had OAI a
No OAI 3.46(3.44,3.48) 3.54(3.52,3.57) 3.07(3.03,3.12)
One OAI 3.03(3.00,3.06) 3.09(3.05,3.12) 2.90(2.84,2.96)
Two OAI 2.93(2.87,2.99) 3.02(2.94,3.10) 2.81(2.72,2.89)
Three OAI 2.38(2.00,2.77) 2.56(2.03,3.09) 2.09(1.57,2.62)
Age at first AD recorded diagnosis relative to OAI
AD preceding asthma 2.92(2.91,2.94) 3.01(3.00,3.04) 2.60(2.57,2.63)
AD preceding seasonal allergies 3.05(3.04,3.07) 3.15(3.13,3.17) 2.70(2.67,2.73)
AD preceding food allergies 3.36(3.25,3.28) 3.678(3.45,3.39) 2.91(2.88,2.94)
AD occurring after asthma 8.40(8.31,8.49) 8.64(8.54,8.75) 7.61(7.44,7.78)
AD occurring after seasonal allergies 10.99(10.84,10.15) 11.30(11.11,11.48) 10.109.83,10.37)
AD occurring after food allergies 6.78(6.51,7.05) 6.59(6.27,6.90) 7.36(6.83,7.89)
a

maternal history of asthma, seasonal allergy and/or food allergy