Table 3.

Performance of clinical scores to predict advanced liver fibrosis (VCTE ≥ 9.7 kPa) and cirrhosis (VCTE ≥ 13.6 kPa) among different racial/ethnic groups in the overall population.

	Hispanic	Non-Hispanic White	Non-Hispanic Black	Non-Hispanic Asian	p value#	Entire cohort
Advanced Fibrosis (F3–4 vs. F0–2)
FIB-4	0.66 (0.60–0.73)	0.63 (0.57–0.68)	0.59 (0.52–0.65)	0.70 (0.59–0.81)	0.25	0.63 (0.60–0.67)
APRI	0.62 (0.55–0.69)	0.63 (0.58–0.68)	0.50 @,$,^ (0.44–0.57)	0.72 (0.60–0.84)	0.004	0.60 (0.57–0.64)
NFS	0.78 (0.73–0.83)	0.76 (0.72–0.80)	0.74 (0.68–0.80)	0.83 (0.74–0.92)	0.36	0.77 (0.74–0.80)
p value*	<0.001	<0.001	<0.001	0.026		<0.001
Cirrhosis (F4 vs. F0–3)
FIB-4	0.78 (0.69–0.87)	0.64 @,^ (0.56–0.72)	0.52 @,^ (0.39–0.65)	0.83 (0.72–0.95)	<0.001	0.67 (0.62–0.72)
APRI	0.65 (0.53–0.77)	0.67 ^ (0.60–0.75)	0.52 $,^ (0.41–0.62)	0.84 @ (0.76–0.93)	<0.001	0.65 (0.60–0.70)
NFS	0.85 (0.79–0.92)	0.78 ^ (0.72–0.84)	0.76 ^ (0.64–0.87)	0.91 (0.83–0.99)	0.046	0.81 (0.77–0.85)
p value*	0.002	<0.001	<0.001	0.34		<0.001

^*p value comparing FIB-4, APRI and NFS.

^#p value comparing performance of each clinical score among different racial/ethnic groups.

^@p<0.05 vs. Hispanic subjects

^$p<0.05 vs. non-Hispanic White subjects

^{^}p<0.05 vs. non-Hispanic Asian subjects