TABLE III.
Univariable analysis and multivariable model for the mAQLQ global score among asthmatic subjects
| Characteristics | Univariable associations | Final multivariable model | ||
|---|---|---|---|---|
| Median (IQR) | P value | Unstandardized β coefficient (95% CI) | P value | |
| Sex* | .007 | |||
| Female | 5.7 (4.9–6.4) | |||
| Male | 6.2 (5.4–6.7) | |||
| Age (y)* | .590 | |||
| <35 | 5.7 (4.9–6.5) | |||
| 35–45 | 6.2 (5.1–6.5) | |||
| ≥45 | 6.2 (5.1–6.5) | |||
| Smoking habit* | .702 | |||
| Never smoked | 6.0 (5.2–6.4) | |||
| Ex-smoker | 5.7 (4.8–6.7) | |||
| Current smoker | 6.1 (5.1–6.5) | |||
| Body mass index (kg/m2)* | .03 | |||
| <25 | 6.3 (5.4–6.6) | |||
| ≥25 | 5.7 (4.9–6.4) | |||
| Education level* | .729 | |||
| >12 y | 6.1 (5.3–6.5) | |||
| ≤12 y | 6.1 (4.9–6.5) | |||
| Current job duration* | .064 | |||
| <5 y | 5.7 (4.3–6.4) | |||
| ≥5 y | 6.0 (5.4–6.5) | |||
| Asthma preexisting to current job | ||||
| Yes | 5.7 (4.9–6.4) | .006 | ||
| No | 6.4 (5.7–6.7) | |||
| Asthma control* | <.001 | |||
| ACT score > 19 | 6.3 (5.7–6.7) | Reference | ||
| ACT score ≤ 19 | 4.8 (3.7–5.4) | −1.4 (−1.8 to −1.1) | <.001 | |
| Asthma* | ||||
| Non-WRA | 6.3 (5.7–6.7) | <.001 | Reference | |
| WRA† | 5.3 (4.2–6.3) | −0.4 (−0.7 to −0.01) | .044 | |
| Asthma medication | .001 | |||
| No | 6.2 (5.5–6.7) | |||
| Yes | 5.4 (4.1–6.3) | |||
| Allergic rhinitis‡ | .282 | |||
| Absent | 6.2 (5.4–6.6) | |||
| Present | 6.0 (5.0–6.5) | |||
| WRR§ | .017 | |||
| Absent | 6.3 (6.1–7.0) | Reference | ||
| Present | 5.6 (5.0–6.4) | −0.4 (−0.8 to −0.02) | .061 | |
| Work-related conjunctivitis|| | .637 | |||
| Absent | 6.0 (5.1–6.5) | |||
| Present | 6.1 (5.1–6.4) | |||
| Chronic phlegm* | .004 | |||
| Absent | 6.1 (5.4–6.5) | |||
| Present | 5.0 (3.9–6.3) | |||
| Depression, physician-based | .677 | |||
| Absent | 6.0 (5.1–6.5) | |||
| Present | 5.9 (4.8–6.5) | |||
| Nonrespiratory, nondepression comorbidity | .393 | |||
| Absent | 6.0 (5.0–6.5) | |||
| Present | 6.1 (5.2–6.6) | |||
IQR, Interquartile range.
Analysis was done in the WRA and non-WRA groups because AQLQ is an asthma-specific questionnaire. Multivariable analysis was done on 106 subjects and incorporated well-known confounders such as age, sex, smoking habits, body mass index, academic level, and current job duration (marked with asterisks) and other covariates with a P value of <.1 in univariable analyses.
Well-known confounders included in the multivariable analysis.
WRA is defined as current asthma associated with ≥2 WRA symptoms.
Allergic rhinitis is defined as either self-reported or physician-based allergic rhinitis.
WRR is defined as current rhinitis with ≥2 WRR symptoms.
Work-related conjunctivitis is defined as red and itchy eyes at work.