TABLE VII.

Univariable analysis and multivariable model for any overall work impairment based on WPAI-GH

Characteristics	Univariable associations		Final multivariable model
	Any overall work impairment, n (%)	P value	OR (95% CI)	P value
Sex*		.034
Female	86 (55.8)		1.4 (0.9–2.1)	.093
Male	68 (44.2)		Reference
Age (y)*		.747
<35	46 (31.1)
35–45	46 (31.1)
≥45	56 (37.8)
Smoking habit*		.035
Never smoked	82 (53.6)
Ex-smoker	38 (24.8)
Current smoker	33 (21.6)
Body mass index (kg/m2)*		.035
<25	65 (45.5)		Reference
≥25	78 (54.5)		1.5 (0.9–2.2)	.055
Education level*		.051
>12 y	72 (47.4)		Reference
≤12 y	80 (52.6)		0.7 (0.5–1.0)	.070
Current job duration*		.986
<5 y	61 (43.0)
≥5 y	81 (57.0)
Asthma preexisting to current job
Yes	42 (87.5)	.229
No	6 (12.5)
Asthma control		.004
ACT score > 19	17 (53.1)
ACT score ≤ 19	15 (46.9)
Asthma*		<.001
Absent	96 (62.3)		Reference
Non-WRA	27 (17.5)		2.0 (1.2–3.5)	.008
WRA†	31 (20.1)		4.5 (2.5–8.1)	<.001
Depression, physician-based		.037
Absent	131 (85.1)		Reference
Present	23 (14.9)		1.8 (0.9–3.3)	.085
Nonrespiratory, nondepression comorbidity		.003
Absent	77 (50.0)		Reference
Present	77 (50.0)		1.9 (1.2–2.9)	.004

Multivariable analysis was done on 713 subjects and incorporated well-known confounders such as age, sex, smoking habits, body mass index, academic level, and current job duration (marked with asterisks) and other covariates with a P value of <.1 in univariable analyses. Asthma control was not included because the information was available only among asthmatic subjects.

^*Well-known confounders included in the multivariable analysis.

^†WRA is defined as current asthma associated with ≥2 WRA symptoms.