Table 2.

Meeting sessions and topic areas.

Keynotes Talks:

• The need for inclusive research – How far have we come? – NIH ORWH

• Research for women’s health – FDA OWH

Session I: Sex differences and model considerations

• Sex differences observed in a variety of nonclinical models (TBI, WTLI, and PBI)

• Sex differences in acute and late effects of radiation

Session II: Radiation research for medical countermeasures – influence of sex on efficacy

• Male and female differences in the effectiveness of, or response to, MCMs

• Sex differences in targeted mechanisms of action, or off-target effects

• Sex differences in animal response to irradiation

Session III: Sex differences in biomarker and biodosimetry development

• Sex differences observed in radiation biodosimetry signatures

• Differences in radiation-induced responses due to sex, sex-linked organ specificity (e.g. lung, GI, heart), and other sex-specific confounders

Session IV: Etiology of sex differences in radiation research outcomes

• Genetic, hormonal, and other sources of sex differences in tissues and biological systems and the response to radiation exposure

• Understanding the biological mechanisms underlying male and female differences that may influence radiation exposure outcomes of targets for biomarker development and therapeutic interventions

Session V: Real-life impacts of sex differences

• Impact of sex differences in a variety of real-world settings, including space flight and nuclear accidents

• Impact of sex and gender differences on national preparedness