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. Author manuscript; available in PMC: 2025 Mar 1.
Published in final edited form as: J Psychiatr Res. 2024 Jan 16;171:108–115. doi: 10.1016/j.jpsychires.2024.01.018

Table 1.

Clusters showing significant functional connectivity with seed which predict CBT response

Region Voxel size MNI Coordinates T BA
x y z

Using PCC seed:
Pre-treatment connectivity predicting greater symptom improvement
 L cerebellum (culmen) 1047 −30 −66 −24 5.84 ---
  L fusiform gyrus −30 −50 −9.5 3.73 37
  L parahippocampus −25.5 −52 −6 3.66 19
  L lingual gyrus −22 −76 −1.5 3.57 18
Pre-treatment connectivity predicting less symptom improvement
 R putamen (lentiform nucleus) 642 +18 +08 +04 −5.36 ---
  R caudate +16 +14 −04 −4.05 ---
Using PCC/precuneus seed:
Pre-treatment connectivity predicting greater symptom improvement
 L cerebellum (culmen) 794 −30 −66 −24 6.01 ---
  L fusiform gyrus −28 −53 −8 3.83 37
  L parahippocampus −28 −53.5 −7.5 3.78 19
  L lingual gyrus −22 −78 −2 3.78 18
  L middle temporal gyrus −56 −56 −7.5 2.91 37
 L insula 361 −44 −10 −6 4.86 13
  L superior temporal gyrus −46.5 −8 −5.5 4.40 22
  L claustrum −40 −10 −5.5 4.25 ---
 L middle occipital gyrus 306 −24 −88 +16 3.90 19
  L cuneus −2 −80 +16 2.85 17
 R postcentral gyrus 292 +62 −20 +50 4.54 2
  R inferior parietal lobule +56 −22 +50 4.15 40
 R precuneus 214 +28 −44 +48 4.12 7
  R superior parietal lobule +30 −47.5 +48 3.35 7
  R paracentral lobule +26 −40.5 +48 2.92 5
Pre-treatment connectivity predicting less symptom improvement
 R putamen 351 +22 +04 −06 −4.70 ---
  R lateral globus pallidus +19 +2 −5 −4.26 ---