. Author manuscript; available in PMC: 2025 Apr 5.

Published in final edited form as: J Comput Chem. 2023 Nov 22;45(9):512–522. doi: 10.1002/jcc.27261

Table 2.

Peptide area fraction ( $ϕ$ ) of simulated asymmetric bilayers.

System	gA-POPC	gA-DNPC	gA4-DNPC	gA4^W2Q-DNPC	gA9-DNPC	9gA-DNPC	FP-POPC
Method
APL	0.04	0.04	0.20	0.19	0.40	0.31	0.08
APL/P2₁	0.06 ( $ϕ_{1}$ )	0.06 ( $ϕ_{1}$ )	0.19 ( $ϕ_{1}$ )	0.18 ( $ϕ_{1}$ )	0.38 ( $ϕ_{1}$ )	0.28 ( $ϕ_{1}$ )	0.08 ( $ϕ_{1}$ )
	0.04 ( $ϕ_{2}$ )	0.04 ( $ϕ_{2}$ )	0.13 ( $ϕ_{2}$ )	0.13 ( $ϕ_{2}$ )	0.22 ( $ϕ_{2}$ )	0.21 ( $ϕ_{2}$ )	0.05 ( $ϕ_{2}$ )
					0.14 ( $ϕ_{3}$ )	0.13 ( $ϕ_{3}$ )

Different peptide area fractions for (APL/P2₁) are denoted by $ϕ_{1}$ , $ϕ_{2}$ , and $ϕ_{3}$ , where $ϕ_{1} > ϕ_{2} {> ϕ}_{3}$ for each peptide-bilayer system.