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. 2005 May 10;33(8):2580–2594. doi: 10.1093/nar/gki536

Figure 5.

Figure 5

PCA, ROC plots and trajectory summary views of clusters from the Cho classification and an unsupervised clustering (EM MoDG) of an Affymetrix yeast cell cycle time course (1). The top panel for each clustering results shows cluster means projected into the top two dimensions of the principle component space defined by the expression data (capturing 64% of the variance). The area of the marker size for each cluster is proportional to the number of genes in each cluster. Below are ROC curves (left) and trajectory summaries (right) for each cluster. The trajectory summaries display every gene's expression profile within a cluster as a blue line with time along the x-axis and expression along the y-axis. The red line within each trajectory summary represents the mean expression level for the cluster. ROC area values are displayed within the ROC curve for each cluster. The background colors for the trajectory summaries and the PCA projection have been matched within each clustering result. In addition, LA was used to find the optimal mapping of clusters between the Cho classification and the EM MoDG result and the colors have been set accordingly.