Table 3.

Secondary outcomes comparison between deep (DP) and high-moderate (HM) hypothermia groups and between low-moderate (LM) and DP hypothermia groups.

	DP vs. HM			LM vs. DP
Change Scores	Mean diff**	97.5% CI	P-value*	Mean diff**	97.5% CI	P-value*
NIHSS	0.12	(−0.05, 0.29)	.15	−0.11	(−0.25, 0.03)	.11
OARS-IADL	0.58	(−0.87, 2.03)	.43	−0.77	(−2.18, 0.64)	.28
CES-D	−1.23	(−3.89, 1.42)	.36	−1.00	(−3.49, 1.50)	.43
DASI	0.10	(−5.27, 5.47)	.97	3.47	(−1.84, 8.79)	.20
STAI	−1.71	(−4.98, ,1.56)	.30	−0.07	(−2.88, 2.73)	.96
Health	−0.12	(−0.46, 0.22)	.50	−0.30	(−0.65, 0.05)	.09
MA	3.25	(−1.61, 8.11)	.19	−0.91	(−5.28, 3.45)	.68
SA	0.04	(−1.06, 1.14)	.94	−0.41	(−1.58, 0.76)	.49
SOCSUP	−3.47	(−7.40, 0.45)	.08	1.43	(−2.82, 5.68)	.51
SCL-90	−0.59	(−1.81, 0.62)	.34	−0.49	(−1.69, 0.72)	.42
Work Activity (WA)	0.41	(−0.90, 1.71)	.54	−0.76	(−2.01, 0.48)	.23
	DP (N=91)	HM (N=92)		LM (N=86)	DP (N=91)
Postoperative Delirium	27 (29.7%)	33 (35.9%)	.37	33 (38.4%)	27 (29.7%)	.22

Abbreviation: NIHSS: NIH Stroke Scale; OARS-IADL: Duke Older American Resources and Services Procedures – Instrumental Activities of Daily Living; CES-D: Center for Epidemiologic Studies Depression Scale; DASI: Duke Activity Status Index; STAI: State Trait Anxiety Inventory; Health: Health score from short form 36; MA: Cognitive difficulty scale; SA: Social activities; SOCSUP: Perceived social support scale; WA: Work activities;

^*These are raw p-values based on two-sided two-sample t-test for QOL and NIHSS outcomes and chi-square test for postoperative delirium. The minimum FDR adjusted p-value for QQL was 0.675 for DP vs. HM and 0.638 for LM vs. DP.

^**Mean diff = mean (DP) – mean (HM) or mean (LM) – mean (DP) for each variable.