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. Author manuscript; available in PMC: 2025 Apr 1.
Published in final edited form as: Contraception. 2024 Jan 15;132:110370. doi: 10.1016/j.contraception.2024.110370

Table 2.

Outcomes of ruptured and unruptured dominant follicles during the five days following randomization to the etonorgestrel implant with or without ulipristal acetate 30mg oral stratified by follicle size on day of randomization.

Implant Only (n=20) Implant + UPA (n=19)
<15mm ≥15mm All <15mm ≥15mm All
Follicular rupture 8 12
Ovulation1 2 5 7 4 8 12
Ovulation dysfunction2 1 1 0
No Follicular Rupture 12 7
Follicular atresia3 1 1 1 1
Persistently enlarged follicle4 7 2 9 1 5 6
Luteinized unruptured follicle5 1 1 2 0
35% ovulation 63% ovulation
1

Ovulation= a follicle ≥15mm that disappears or decreases in size by >50% and serum progesterone >3 ng/mL. It MAY be preceded 24–48 h by an LH surge (≥21 IU/L)

2

Ovulation dysfunction= a follicle ≥15mm that disappears or decreases in size by >50% but not proceeded by an LH surge or preceded by a blunted (<21 IU/L) LH surge and without any progesterone >3 ng/mL

3

Follicular atresia = a follicle <15 mm with arrest in growth or decrease in size of <50% without any progesterone >3 ng/mL

4

Persistently enlarged follicle = a follicle measuring ≥15 mm that persists for at least one week without any progesterone >3 ng/mL

5

Luteinized unruptured follicle= a follicle ≥15 mm that persists for at least one week with at least one progesterone >3 ng/mL