Table 2:

Multivariable associations between alcohol and drug use and fall, number of falls, fracture, and ED/hospitalization for a fall or fracture among people with HIV ^a

	Fall, any	Number of falls b	Fracture, any	ED/hospitalization for a fall or fracture
Alcohol use
Heavy use, any c	1.49 (1.08, 2.07)	1.55 (1.10, 2.19)	1.23 (0.66, 2.27)	1.81 (1.10, 2.97)
Average daily consumption d	1.04 (0.99, 1.09)	1.08 (1.03, 1.13)	1.08 (1.00, 1.17)	1.07 (0.99, 1.15)
Number of heavy drinking days e	1.03 (0.99, 1.07)	1.05 (1.01, 1.10)	1.07 (1.00, 1.16)	1.06 (1.00, 1.13)
Illicit drug use f
Opioid use	1.38 (0.88, 2.16)	1.17 (0.69, 1.99)	2.22 (1.08, 4.57)	0.88 (0.39, 1.98)
Sedative use	1.73 (1.01, 2.96)	2.21 (1.32, 3.71)	1.66 (0.55, 5.05)	2.54 (1.12, 5.80)
Cocaine use	0.76 (0.46, 1.24)	1.13 (0.65, 1.95)	1.15 (0.44, 2.99)	0.67 (0.34, 1.32)

^aAdjusted Odds Ratios (95% Confidence Intervals) were calculated using separate GEE logistic regression models for each dichotomous outcome and GEE ordinal logistic regression for the outcome, number of falls. All models include one alcohol measure, opioid, sedative, cocaine use (as 3 separate measures), demographics, homelessness, HIV disease markers, body mass index, and depressive symptoms. AOR for opioid, sedative, and cocaine use presented in this table are results of the multivariable regression analyses of heavy alcohol use. Bolded text indicates p<0.05.

^bNumber of falls was a categorical variable: 0, 1, 2, or ≥3 falls. AOR indicates odds of reporting a higher category of number of falls

^cTimeline Follow back, past 14-day use. Exceeds NIAAA weekly limits (>7 drinks/week for women, >14 drinks/week for men) or daily limits (4+ drinks in one day for women, 5+ in one day for men).

^dAdjusted Odds Ratio for an increase of 14 grams per day

^eAdjusted Odds Ratio for each additional day of heavy alcohol use (exceeding daily limit).

^fAddiction Severity Index, past 30 days. Parameter estimates for each drug type are reported from the model of heavy alcohol use