Table 2.

TAS2Rs in the human reproductive system

Receptor	Tissue or cell type	method	reference
TAS2R3, TAS2R4, TAS2R14, TAS2R19, and TAS2R43	testis and sperm	qRT-PCR, western blot, and immunostaining	Governini et al., 2020
TAS2R3, TAS2R4, TAS2R14, TAS2R19, and TAS2R43	freshly isolated granulosa cells and cumulus cells	qRT-PCR, western blot, immunostaining	Semplici et al., 2021
TAS2R3, TAS2R4, TAS2R14, TAS2R19, and TAS2R43	immortalized primary follicular granulosa cells hGL5	qRT-PCR, western blot, immunostaining	Luongo et al., 2022
TAS2R1, TAS2R4, TAS2R10, TAS2R14, and TAS2R38	fallopian tube tissue, normal uterine tissue, ovarian cystadenocarcinoma tumor tissue, human ovarian cancer cell line (OVCAR4 and OVCAR8), ovarian clear cell carcinoma cell lines SKOV3, prostate cancer cell lines (DU145, LNCaP, and PC3), benign prostatic hyperplasia cells line BPH-1, and endometrial cancer cell line HEC-1a	qRT-PCR, western blot	Martin et al., 2019
TAS2R4, TAS2R5, TAS2R10, TAS2R13, and TAS2R14	fresh human myometrium	qRT-PCR	Zheng et al., 2017
TAS2R3, TAS2R4, TAS2R5, TAS2R7, TAS2R8, TAS2R10, TAS2R13, TAS2R14, TAS2R31, TAS2R39, TAS2R42, TAS2R43, TAS2R45, and TAS2R50	human myometrial cell line hTERT-HM	qRT-PCR	Zheng et al., 2017
TAS2R38	endocervix, placenta, and placenta cell line JEG-3	immunostaining	Wölfle et al., 2016
TAS2R14	placenta, trophoblast cell line HTR-8/Svneo, and trophoblast-derived choriocarcinoma cells JAR, JEG, and BeWo.	PCR, immunostaining	Taher et al., 2019