Table 2.
Heart Function at Study Entry, All Subjects
| Characteristic | |||
|---|---|---|---|
| Mean ± SD or frequency (%) | Control (n = 8) | Severe PreE (n = 14) | P Value |
| LVEF (%) | 60 ± 5 | 59 ± 5 | 0.541 |
| LV Fractional shortening (%) | 36 ± 4 | 34 ± 6 | 0.517 |
| LV Septum (cm) | 0.92 ± 0.17 | 1.00 ± 0.13 | 0.240 |
| LV Posterior Wall (cm) | 0.93 ± 0.09 | 1.01 ± 0.03 | 0.102 |
| LV, GLS (%) | −21 ± 3 | −20 ± 3 | 0.241 |
| LV, GLS >−18% | 0 (0%) | 5 (36%) | 0.028 |
| LV, Tei Index | 0.43 ± 0.07 | 0.53 ± 0.13 | 0.066 |
| Mitral E Velocity (cm/sec) | 89 ± 17 | 82 ± 13 | 0.368 |
| Mitral A Velocity (cm/sec) | 59 ± 8 | 73 ± 6 | 0.172 |
| Mitral e’ Velocity (cm/sec) | 13.2 ± 2.3 | 11.0 ± 2.2 | 0.022 |
| Mitral E/e’ | 6.8 ± 1.4 | 8.0 ± 1.9 | 0.120 |
| Mitral E/A | 1.6 ± 0.5 | 1.2 ± 0.3 | 0.054 |
| Mitral Deceleration Time (msec) | 212 ± 31 | 171 ± 41 | 0.018 |
| RV Length (cm) | 7.2 ± 0.3 | 7.5 ± 0.2 | 0.581 |
| RV Base (cm) | 4.0 ± 0.5 | 3.8 ± 0.6 | 0.446 |
| RV, FAC (%) | 45 ± 9 | 46 ± 8 | 0.783 |
| TAPSE (cm) | 2.5 ± 0.4 | 2.5 ± 0.4 | 0.986 |
| RV S’ (cm) | 13.8 ± 1.3 | 15.7 ± 3.1 | 0.057 |
| RV, GLS (%) | −25 ± 5 | −23 ± 3 | 0.365 |
| LA Volume (mL) | 42 ± 15 | 51 ± 10 | 0.173 |
| LA Volume, indexed (mL/m2) | 22 ± 8 | 26 ± 5 | 0.268 |
| RA Volume (mL) | 38 ± 9 | 37 ± 3 | 0.858 |
| RA Volume, indexed (mL/m2) | 20 ± 4 | 18 ± 5 | 0.428 |
FAC: Fractional area change, G+ = cardiomyopathy gene positive, G− = cardiomyopathy gene negative, GLS: global longitudinal strain, LA: left atrium, LV: left ventricle, LVEF: left ventricular ejection fraction, PreE: pre-eclampsia, RA: right atrium, RV: right ventricle, SD: standard deviation, TAPSE: tricuspid annular plane systolic excursion